Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Putative acyl-CoA hydrolase

Gene

NMC1417

Organism
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 561Coenzyme A 2; via carbonyl oxygenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Enzyme and pathway databases

BioCyciNMEN272831:GJDX-1336-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative acyl-CoA hydrolaseImported
Gene namesi
Ordered Locus Names:NMC1417Imported
OrganismiNeisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)Imported
Taxonomic identifieri272831 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000002286 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi137 ↔ 158Interchain (with C-158 in A1KUS8)Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IENX-ray2.00A/B/C/D1-160[»]
ProteinModelPortaliA1KUS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni64 – 674Coenzyme A 1 bindingCombined sources
Regioni85 – 873Coenzyme A 2 bindingCombined sources
Regioni146 – 1494Coenzyme A 2 bindingCombined sources

Phylogenomic databases

eggNOGiCOG1607.
HOGENOMiHOG000044842.
OMAiRYCGKGT.
OrthoDBiEOG65XN1H.

Family and domain databases

Gene3Di3.10.129.10. 1 hit.
InterProiIPR029069. HotDog_dom.
IPR006683. Thioestr_supf.
[Graphical view]
PfamiPF03061. 4HBT. 1 hit.
[Graphical view]
SUPFAMiSSF54637. SSF54637. 1 hit.

Sequencei

Sequence statusi: Complete.

A1KUS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQQRQLPSH ELIMSELMMP DTANFSGNVH GGELLLLLDQ VAYSCASRYS
60 70 80 90 100
GNYCVTLSVD KVLFKEPIHI GDLVTFYAAV NYTGRTSMEI GIRVEAQNIR
110 120 130 140 150
TGEIRHTNSC YFTMVAVKDG KPVPVPPLEI LTDRQRCRYE KAKKRRDISL
160
QASEDMSCGC
Length:160
Mass (Da):17,982
Last modified:February 6, 2007 - v1
Checksum:i9EA969FF4903C27E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM421808 Genomic DNA. Translation: CAM10627.1.
RefSeqiWP_002216871.1. NC_008767.1.
YP_975407.1. NC_008767.1.

Genome annotation databases

EnsemblBacteriaiCAM10627; CAM10627; NMC1417.
KEGGinmc:NMC1417.
PATRICi20352958. VBINeiMen17609_1724.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM421808 Genomic DNA. Translation: CAM10627.1.
RefSeqiWP_002216871.1. NC_008767.1.
YP_975407.1. NC_008767.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IENX-ray2.00A/B/C/D1-160[»]
ProteinModelPortaliA1KUS8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM10627; CAM10627; NMC1417.
KEGGinmc:NMC1417.
PATRICi20352958. VBINeiMen17609_1724.

Phylogenomic databases

eggNOGiCOG1607.
HOGENOMiHOG000044842.
OMAiRYCGKGT.
OrthoDBiEOG65XN1H.

Enzyme and pathway databases

BioCyciNMEN272831:GJDX-1336-MONOMER.

Family and domain databases

Gene3Di3.10.129.10. 1 hit.
InterProiIPR029069. HotDog_dom.
IPR006683. Thioestr_supf.
[Graphical view]
PfamiPF03061. 4HBT. 1 hit.
[Graphical view]
SUPFAMiSSF54637. SSF54637. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700532 / DSM 15464 / FAM18Imported.
  2. "Expression, purification and crystallization of acetyl-CoA hydrolase from Neisseria meningitidis."
    Khandokar Y.B., Londhe A., Patil S., Forwood J.K.
    Acta Crystallogr. F 69:1303-1306(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH COENZYME A, DISULFIDE BONDS.

Entry informationi

Entry nameiA1KUS8_NEIMF
AccessioniPrimary (citable) accession number: A1KUS8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 24, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.