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Protein
Submitted name:

Alpha 2,8-sialyltransferase ST8Sia IV

Gene

St8sia4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Source: Ensembl
  • sialyltransferase activity Source: RGD

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseSAAS annotationImported, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-4085001 Sialic acid metabolism
R-RNO-419037 NCAM1 interactions

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha 2,8-sialyltransferase ST8Sia IVImported
Submitted name:
RCG55449Imported
Submitted name:
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4Imported
Gene namesi
Name:St8sia4Imported
Synonyms:LOC501189Imported, Siat 8DImported
ORF Names:rCG_55449Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi621845 St8sia4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi237 ↔ 387UniRule annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000019128

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026010

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
GeneTreeiENSGT00550000074407
HOVERGENiHBG056466
KOiK06614
OMAiHSVEGWK
OrthoDBiEOG091G0AL4

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 1 hit

Sequencei

Sequence statusi: Complete.

A1KQY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHKVSHLKRN PSPREAAQSD PSPASANCAA GRWAALENRE SSTAERPSDL
60 70 80 90 100
ILGSRLHAPF ANFRFLPLDY FPKTEPLYQE KVPELGQPGL SRAPKMRSIR
110 120 130 140 150
KRWTICTISL LLIFYKTKEI ARTEEHQETQ LIGDGELCLS RSLVNNSDKI
160 170 180 190 200
TRKAGSTIFQ HSVQGWKINS SLVLEIRKNI LRFLDAERDV SVVKSSFKPG
210 220 230 240 250
DVIHYVLDRR RTLNISHDLH SLLPEVSPMK NRRFKTCAVV GNSGILLDSG
260 270 280 290 300
CGKEIDSHNF VIRCNLAPVV EFAADVGTKS DFITMNPSVV QRAFGGFRNE
310 320 330 340 350
SDREKFVHRL SMLNDSVLWI PAFMVKGGEK HVEWVNALIL KNKLKVRTAY
360 370 380 390 400
PSLRLIHAVR GYWLTNKVPI KRPSTGLLMY TLATRFCDEI HLYGFWPFPK
410 420 430 440 450
DLNGKAVKYH YYDDLKYRYF SNASPHRMPL EFKTLNVLHN RGALKLTTGK

CMKQ
Length:454
Mass (Da):51,762
Last modified:February 6, 2007 - v1
Checksum:i4644DA8D857E7D36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07068398 Genomic DNA No translation available.
AABR07068399 Genomic DNA No translation available.
AM419015 mRNA Translation: CAL91579.1
CH473997 Genomic DNA Translation: EDL91890.1
RefSeqiNP_446366.1, NM_053914.1
UniGeneiRn.234502

Genome annotation databases

EnsembliENSRNOT00000026010; ENSRNOP00000026010; ENSRNOG00000019128
GeneIDi116696
KEGGirno:116696

Similar proteinsi

Entry informationi

Entry nameiA1KQY6_RAT
AccessioniPrimary (citable) accession number: A1KQY6
Secondary accession number(s): F1MA57
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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