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A1KNN0 (A1KNN0_MYCBP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase RuleBase RU000531 HAMAP MF_00210
EC=2.5.1.19 RuleBase RU000531 HAMAP MF_00210
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA_1 EMBL CAL73246.1
Synonyms:aroA1 HAMAP MF_00210, aroA_2 EMBL CAL73339.1
Ordered Locus Names:BCG_3257, BCG_3350
OrganismMycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP]
Taxonomic identifier410289 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. RuleBase RU000531 HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. RuleBase RU004164 HAMAP MF_00210

Sequences

Sequence LengthMass (Da)Tools
A1KNN0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 27BB86F9412A07D5

FASTA45046,426
        10         20         30         40         50         60 
MKTWPAPTAP TPVRATVTVP GSKSQTNRAL VLAALAAAQG RGASTISGAL RSRDTELMLD 

        70         80         90        100        110        120 
ALQTLGLRVD GVGSELTVSG RIEPGPGARV DCGLAGTVLR FVPPLAALGS VPVTFDGDQQ 

       130        140        150        160        170        180 
ARGRPIAPLL DALRELGVAV DGTGLPFRVR GNGSLAGGTV AIDASASSQF VSGLLLSAAS 

       190        200        210        220        230        240 
FTDGLTVQHT GSSLPSAPHI AMTAAMLRQA GVDIDDSTPN RWQVRPGPVA ARRWDIEPDL 

       250        260        270        280        290        300 
TNAVAFLSAA VVSGGTVRIT GWPRVSVQPA DHILAILRQL NAVVIHADSS LEVRGPTGYD 

       310        320        330        340        350        360 
GFDVDLRAVG ELTPSVAALA ALASPGSVSR LSGIAHLRGH ETDRLAALST EINRLGGTCR 

       370        380        390        400        410        420 
ETPDGLVITA TPLRPGIWRA YADHRMAMAG AIIGLRVAGV EVDDIAATTK TLPEFPRLWA 

       430        440        450 
EMVGPGQGWG YPQPRSGQRA RRATGQGSGG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM408590 Genomic DNA. Translation: CAL73246.1.
AM408590 Genomic DNA. Translation: CAL73339.1.
RefSeqYP_979341.1. NC_008769.1.
YP_979433.1. NC_008769.1.

3D structure databases

ProteinModelPortalA1KNN0.
SMRA1KNN0. Positions 1-424.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1KNN0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000021345; EBMYCP00000021095; EBMYCG00000021340.
EBMYCT00000021978; EBMYCP00000021728; EBMYCG00000021973.
GeneID4698554.
4698762.
GenomeReviewsGene locus BCG_3257 in contig AM408590_GR.
Gene locus BCG_3350 in contig AM408590_GR.
KEGGmbb:BCG_3257.
mbb:BCG_3350.
PATRIC18017634. VBIMycBov80988_3559.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
GeneTreeEBGT00050000016231.
HOGENOMHBG646626.
OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1KNN0_MYCBP
AccessionPrimary (citable) accession number: A1KNN0
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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