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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei81Charge relay systemUniRule annotation1
Active sitei156Charge relay systemUniRule annotation1
Active sitei180Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:BCG_3033c
OrganismiMycobacterium bovis (strain BCG / Pasteur 1173P2)
Taxonomic identifieri410289 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001472 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000158661 – 494Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST494

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA1KN06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1KN06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDIIRSDAA TLAAKIAIKE VSSTEITRAC LDQIEATDET YHAFLHVAAD
60 70 80 90 100
EALAAAAAVD KQVAAGEPLP SALAGVPLAL KDVFTTSDMP TTCGSKILEG
110 120 130 140 150
WRSPYDATLT ARLRAAGIPI LGKTNMDEFA MGSSTENSAY GPTRNPWNLD
160 170 180 190 200
RVPGGSGGGS AAALAAFQAP LAIGSDTGGS IRQPAALTAT VGVKPTYGTV
210 220 230 240 250
SRYGLVACAS SLDQGGPCAR TVLDTALLHQ VIAGHDPRDS TSVDAEVPDV
260 270 280 290 300
VGAARAGAVG DLRGVRVGVV RQLHGGEGYQ PGVLASFEAA VEQLTALGAE
310 320 330 340 350
VSEVDCPHFD HALAAYYLIL PSEVSSNLAR FDAMRYGLRV GDDGTRSAEE
360 370 380 390 400
VMAMTRAAGF GPEVKRRIMI GTYALSAGYY DAYYNQAQKV RTLIARDLDA
410 420 430 440 450
AYRSVDVLVS PTTPTTAFRL GEKVDDPLAM YLFDLCTLPL NLAGHCGMSV
460 470 480 490
PSGLSPDDGL PVGLQIMAPA LADDRLYRVG AAYEAARGPL LSAI
Length:494
Mass (Da):51,436
Last modified:February 6, 2007 - v1
Checksum:iFE9F74EAAE74CE4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM408590 Genomic DNA. Translation: CAL73022.1.
RefSeqiWP_010950812.1. NC_008769.1.

Genome annotation databases

EnsemblBacteriaiCAL73022; CAL73022; BCG_3033c.
KEGGimbb:BCG_3033c.
PATRICi18017144. VBIMycBov80988_3316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM408590 Genomic DNA. Translation: CAL73022.1.
RefSeqiWP_010950812.1. NC_008769.1.

3D structure databases

ProteinModelPortaliA1KN06.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL73022; CAL73022; BCG_3033c.
KEGGimbb:BCG_3033c.
PATRICi18017144. VBIMycBov80988_3316.

Phylogenomic databases

HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGATA_MYCBP
AccessioniPrimary (citable) accession number: A1KN06
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.