A1KMA5 (A1KMA5_MYCBP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable dihydrofolate reductase dfrA EMBL CAL72768.1
EC=1.5.1.3 EMBL CAL72768.1

Gene names

Name:	dfrA EMBL CAL72768.1
Ordered Locus Names:	BCG_2780c

Organism

Mycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP]

Taxonomic identifier

410289 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAL72768.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1KMA5 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: F17C038F1B773797	FASTA	159	17,640
	10 20 30 40 50 60 MVGLIWAQAT SGVIGRGGDI PWRLPEDQAH FREITMGHTI VMGRRTWDSL PAKVRPLPGR 70 80 90 100 110 120 RNVVLSRQAD FMASGAEVVG SLEEALTSPE TWVIGGGQVY ALALPYATRC EVTEVDIGLP 130 140 150 REAGDALAPV LDETWRGETG EWRFSRSGLR YRLYSYHRS

References

[1]

"Genome plasticity of BCG and impact on vaccine efficacy." Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T. Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007) [PubMed: 17372194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM408590 Genomic DNA. Translation: CAL72768.1.
RefSeq	YP_978866.1. NC_008769.1.
3D structure databases
ProteinModelPortal	A1KMA5.
SMR	A1KMA5. Positions 1-159.
ModBase	Search...
Protein-protein interaction databases
STRING	A1KMA5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000020405; EBMYCP00000020155; EBMYCG00000020400.
GeneID	4699078.
GenomeReviews	Gene locus BCG_2780c in contig AM408590_GR.
KEGG	mbb:BCG_2780c.
PATRIC	18016560. VBIMycBov80988_3026.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
GeneTree	EBGT00050000017411.
HOGENOM	HBG665708.
OMA	HATRCEV.
ProtClustDB	CLSK792062.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1KMA5_MYCBP

Accession

Primary (citable) accession number: A1KMA5

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)