A1KLD3 (A1KLD3_MYCBP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamine-dependent NAD(+) synthetase nadE EMBL CAL72445.1
EC=6.3.5.1 EMBL CAL72445.1

Gene names

Name:	nadE EMBL CAL72445.1
Ordered Locus Names:	BCG_2457c

Organism

Mycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP] EMBL CAL72445.1

Taxonomic identifier

410289 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium bovis › Mycobacterium bovis BCG

Protein attributes

Sequence length	679 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL CAL72445.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: EC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1KLD3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 14AC29CE434A8B0D	FASTA	679	74,683
	10 20 30 40 50 60 MNFYSAYQHG FVRVAACTHH TTIGDPAANA ASVLDMARAC HDDGAALAVF PELTLSGYSI 70 80 90 100 110 120 EDVLLQDSLL DAVEDALLDL VTESADLLPV LVVGAPLRHR HRIYNTAVVI HRGAVLGVVP 130 140 150 160 170 180 KSYLPTYREF YERRQMAPGD GERGTIRIGG ADVAFGTDLL FAASDLPGFV LHVEICEDMF 190 200 210 220 230 240 VPMPPSAEAA LAGATVLANL SGSPITIGRA EDRRLLARSA SARCLAAYVY AAAGEGESTT 250 260 270 280 290 300 DLAWDGQTMI WENGALLAES ERFPKGVRRS VADVDTELLR SERLRMGTFD DNRRHHRELT 310 320 330 340 350 360 ESFRRIDFAL DPPAGDIGLL REVERFPFVP ADPQRLQQDC YEAYNIQVSG LEQRLRALDY 370 380 390 400 410 420 PKVVIGVSGG LDSTHALIVA THAMDREGRP RSDILAFALP GFATGEHTKN NAIKLARALG 430 440 450 460 470 480 VTFSEIDIGD TARLMLHTIG HPYSVGEKVY DVTFENVQAG LRTDYLFRIA NQRGGIVLGT 490 500 510 520 530 540 GDLSELALGW STYGVGDQMS HYNVNAGVPK TLIQHLIRWV ISAGEFGEKV GEVLQSVLDT 550 560 570 580 590 600 EITPELIPTG EEELQSSEAK VGPFALQDFS LFQVLRYGFR PSKIAFLAWH AWNDAERGNW 610 620 630 640 650 660 PPGFPKSERP SYSLAEIRHW LQIFVQRFYS FSQFKRSALP NGPKVSHGGA LSPRGDWRAP 670 SDMSARIWLD QIDREVPKG

References

[1]

"Genome plasticity of BCG and impact on vaccine efficacy." Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T. Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BCG / Pasteur 1173P2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM408590 Genomic DNA. Translation: CAL72445.1.
RefSeq	YP_978544.1. NC_008769.1.
3D structure databases
ProteinModelPortal	A1KLD3.
SMR	A1KLD3. Positions 1-679.
ModBase	Search...
Protein-protein interaction databases
STRING	410289.BCG_2457c.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAL72445; CAL72445; BCG_2457c.
GeneID	4695812.
KEGG	mbb:BCG_2457c.
PATRIC	18015860. VBIMycBov80988_2686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0388.
HOGENOM	HOG000051304.
KO	K01950.
OMA	FLALHAW.
ProtClustDB	PRK02628.
Enzyme and pathway databases
BioCyc	MBOV410289:GJW7-2488-MONOMER.
Family and domain databases
Gene3D	3.40.50.620. 2 hits. 3.60.110.10. 1 hit.
InterPro	IPR003010. C-N_Hydrolase. IPR014445. Gln-dep_NAD_synthase. IPR022310. NAD/GMP_synthase. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Pfam	PF00795. CN_hydrolase. 1 hit. PF02540. NAD_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF006630. NADS_GAT. 1 hit.
SUPFAM	SSF56317. Ntlse/CNhydtse. 1 hit.
PROSITE	PS50263. CN_HYDROLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1KLD3_MYCBP

Accession

Primary (citable) accession number: A1KLD3

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)