A1KIS4 (A1KIS4_MYCBP) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 40.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094 EC=1.3.1.9 PIRNR PIRNR000094 | ||||
| Gene names |
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| Organism | Mycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 410289 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 269 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094 |
| Pathway | Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094 |
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis |
| Ligand | NAD PIRNR PIRNR000094 |
| Molecular function | Oxidoreductase PIRNR PIRNR000094 EMBL CAL71533.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 158 | 1 | Proton acceptor By similarity PIRSR PIRSR000094-1 | ||||||
Sequences
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References
| [1] | "Genome plasticity of BCG and impact on vaccine efficacy." Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T. Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007) [PubMed: 17372194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AM408590 Genomic DNA. Translation: CAL71533.1. |
| RefSeq | YP_977638.1. NC_008769.1. |
3D structure databases | |
| ProteinModelPortal | A1KIS4. |
| SMR | A1KIS4. Positions 2-269. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A1KIS4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000021805; EBMYCP00000021555; EBMYCG00000021800. |
| GeneID | 4696660. |
| GenomeReviews | Gene locus BCG_1546 in contig AM408590_GR. |
| KEGG | mbb:BCG_1546. |
| PATRIC | 18013860. VBIMycBov80988_1691. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0623. |
| GeneTree | EBGT00050000015205. |
| HOGENOM | HBG750976. |
| OMA | DCDVGSD. |
| ProtClustDB | PRK07889. |
Family and domain databases | |
| InterPro | IPR014358. Enoyl-ACP_Rdtase_NADH. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| KO | K11611. |
| PIRSF | PIRSF000094. Enoyl-ACP_rdct. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | A1KIS4_MYCBP | ||||||||
| Accession | Primary (citable) accession number: A1KIS4 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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