A1KGJ6 (RL24_MYCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L24

Gene names

Name:	rplX
Ordered Locus Names:	BCG_0765

Organism

Mycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP]

Taxonomic identifier

410289 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP MF_01326_B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit By similarity. HAMAP MF_01326_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L24P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	50S ribosomal protein L24 HAMAP MF_01326_B		PRO_1000052258

Sequences

	Sequence		Length	Mass (Da)
	A1KGJ6 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 20AC100C291EC319	FASTA	105	11,475
	10 20 30 40 50 60 MKVHKGDTVL VISGKDKGAK GKVLQAYPDR NRVLVEGVNR IKKHTAISTT QRGARSGGIV 70 80 90 100 TQEAPIHVSN VMVVDSDGKP TRIGYRVDEE TGKRVRISKR NGKDI

References

[1]

"Genome plasticity of BCG and impact on vaccine efficacy." Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T. Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007) [PubMed: 17372194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BCG / Pasteur 1173P2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM408590 Genomic DNA. Translation: CAL70751.1.
RefSeq	YP_976860.1. NC_008769.1.
3D structure databases
ProteinModelPortal	A1KGJ6.
ModBase	Search...
Protein-protein interaction databases
STRING	A1KGJ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000019408; EBMYCP00000019158; EBMYCG00000019403.
GeneID	4695889.
GenomeReviews	Gene locus BCG_0765 in contig AM408590_GR.
KEGG	mbb:BCG_0765.
PATRIC	18012115. VBIMycBov80988_0833.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0198.
GeneTree	EBGT00050000016303.
HOGENOM	HBG588578.
OMA	KPTRVGY.
ProtClustDB	PRK00004.
Enzyme and pathway databases
BioCyc	MBOV410289:BCG_0765-MONOMER.
Family and domain databases
HAMAP	MF_01326_B. Ribosomal_L24_B. [Tree]
InterPro	IPR005824. KOW. IPR003256. Ribosomal_L24. IPR005825. Ribosomal_L24/26_CS. IPR014723. Ribosomal_L24_SH3-like. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.30.30.200. Ribosomal_L24_SH3-like. 1 hit.
KO	K02895.
PANTHER	PTHR12903. Ribosomal_L24. 1 hit.
Pfam	PF00467. KOW. 1 hit. [Graphical view]
SMART	SM00739. KOW. 1 hit. [Graphical view]
SUPFAM	SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR01079. RplX_bact. 1 hit.
PROSITE	PS01108. RIBOSOMAL_L24. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL24_MYCBP

Accession

Primary (citable) accession number: A1KGJ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program