A1KFN0 (A1KFN0_MYCBP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase PIRNR PIRNR006107
EC=2.3.1.8 PIRNR PIRNR006107

Alternative name(s):
Phosphotransacetylase PIRNR PIRNR006107

Gene names

Name:	pta EMBL CAL70432.1
Ordered Locus Names:	BCG_0447

Organism

Mycobacterium bovis (strain BCG / Pasteur 1173P2) [Complete proteome] [HAMAP]

Taxonomic identifier

410289 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	690 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in acetate metabolism By similarity. PIRNR PIRNR006107
Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate. PIRNR PIRNR006107
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2. PIRNR PIRNR006107
Subcellular location	Cytoplasm By similarity PIRNR PIRNR006107.
Domain	The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity. PIRNR PIRNR006107
Sequence similarities	In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. PIRNR PIRNR006107 In the N-terminal section; belongs to the CobB/CobQ family. PIRNR PIRNR006107

Ontologies

Keywords
Cellular component	Cytoplasm PIRNR PIRNR006107
Molecular function	Acyltransferase PIRNR PIRNR006107 EMBL CAL70432.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1KFN0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: C1061C6DE8DC4ACE	FASTA	690	72,963
	10 20 30 40 50 60 MADSSAIYLA APESQTGKST IALGLLHRLT AMVAKVGVFR PITRLSAERD YILELLLAHT 70 80 90 100 110 120 SAGLPYERCV GVTYQQLHAD RDDAIAEIVD SYHAMADECD AVVVVGSDYT DVTSPTELSV 130 140 150 160 170 180 NARIAVNLGA PVLLTVRAKD RTPDQVASVV EVCLAELDTQ RAHTAAVVAN RCELSAIPAV 190 200 210 220 230 240 TDALRRFTPP SYVVPEEPLL SAPTVAELTQ AVNGAVVSGD VALREREVMG VLAAGMTADH 250 260 270 280 290 300 VLERLTDGMA VITPGDRSDV VLAVASAHAA EGFPSLSCIV LNGGFQLHPA IAALVSGLRL 310 320 330 340 350 360 RLPVIATALG TYDTASAAAS ARGLVTATSQ RKIDTALELM DRHVDVAGLL AQLTIPIPTV 370 380 390 400 410 420 TTPQMFTYRL LQQARSDLMR IVLPEGDDDR ILKSAGRLLQ RGIVDLTILG DEAKVRLRAA 430 440 450 460 470 480 ELGVDLDGAT VIEPCASELH DQFADQYAQL RKAKGITVEH AREIMNDATY FGTMLVHNCH 490 500 510 520 530 540 ADGMVSGAAH TTAHTVRPAL EIIKTVPGIS TVSSIFLMCL PDRVLAYGDC AIIPNPTVEQ 550 560 570 580 590 600 LADIAICSAR TAAQFGIEPR VAMLSYSTGD SGKGADVDKV RAATELVRAR EPQLPVEGPI 610 620 630 640 650 660 QYDAAVEPSV AATKLRDSPV AGRATVLIFP DLNTGNNTYK AVQRSAGAIA IGPVLQGLRK 670 680 690 PVNDLSRGAL VDDIVNTVAI TAIQAQGVHE

References

[1]

"Genome plasticity of BCG and impact on vaccine efficacy." Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T. Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007) [PubMed: 17372194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM408590 Genomic DNA. Translation: CAL70432.1.
RefSeq	YP_976545.1. NC_008769.1.
3D structure databases
ProteinModelPortal	A1KFN0.
ModBase	Search...
Protein-protein interaction databases
STRING	A1KFN0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000021421; EBMYCP00000021171; EBMYCG00000021416.
GeneID	4695793.
GenomeReviews	Gene locus BCG_0447 in contig AM408590_GR.
KEGG	mbb:BCG_0447.
PATRIC	18011409. VBIMycBov80988_0484.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0857.
GeneTree	EBGT00050000017507.
HOGENOM	HBG576804.
OMA	VTPLMFE.
ProtClustDB	PRK05632.
Family and domain databases
InterPro	IPR010766. DRTGG. IPR016475. P-Actrans_bac. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K13788.
Pfam	PF07085. DRTGG. 1 hit. PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1KFN0_MYCBP

Accession

Primary (citable) accession number: A1KFN0

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)