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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Azoarcus sp. (strain BH72)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciASP62928:G1GJH-2243-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:azo2208
OrganismiAzoarcus sp. (strain BH72)
Taxonomic identifieri62928 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesZoogloeaceaeAzoarcus
Proteomesi
  • UP000002588 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003043251 – 235Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST235

Interactioni

Protein-protein interaction databases

STRINGi62928.azo2208

Structurei

3D structure databases

ProteinModelPortaliA1K7M0
SMRiA1K7M0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A1K7M0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPWLTDRPA FPPVERALTE PNGLLAAGGR LTPEWLLAAY RRGIFPWYSD
60 70 80 90 100
GEPILWWSPD PRLVLQPAQI RITRSLRKVL RGRRFEVRFD TAFARVIEEC
110 120 130 140 150
AAPREPGGGT WITPEIRAAY LRMHELGYAH SVESWLDGRL VGGLYGMALG
160 170 180 190 200
RAFFGESMFS RVSDASKVAL AHLARFLEQR DFGVIDCQMT TPHLLSMGAH
210 220 230
EIARREFCAG LERWTVEGPP PAKWSGTTAA EFDWN
Length:235
Mass (Da):26,537
Last modified:February 6, 2007 - v1
Checksum:i033FA647ADDC849A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406670 Genomic DNA Translation: CAL94825.1
RefSeqiWP_011765939.1, NC_008702.1

Genome annotation databases

EnsemblBacteriaiCAL94825; CAL94825; azo2208
KEGGiazo:azo2208

Similar proteinsi

Entry informationi

Entry nameiLFTR_AZOSB
AccessioniPrimary (citable) accession number: A1K7M0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 6, 2007
Last modified: February 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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