Reviewed, UniProtKB/Swiss-Prot A1K5A1 (GLMM_AZOSB)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	azo1389

Organism

Azoarcus sp. (strain BH72) [Complete proteome] [HAMAP]

Taxonomic identifier

62928 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus

Protein attributes

Sequence length	451 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 451	451	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000301278
Sites
	Active site	107	1	Phosphoserine intermediate By similarity
	Metal binding	107	1	Magnesium; via phosphate group By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
	Metal binding	250	1	Magnesium By similarity
Amino acid modifications
	Modified residue	107	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1K5A1-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 0C6B090762F57776	FASTA	451	48,059
	10 20 30 40 50 60 MARKYFGTDG VRGRVGELPI TPEFVMRLGY AAGVTLVARE HLPAGERPAI LIGKDTRVSG 70 80 90 100 110 120 YMLEAALQAG FAAAGVDVLL AGPIPTPAVA YLTRALRLQA GVVISASHNP FYDNGIKFFS 130 140 150 160 170 180 AGGAKLPDAV EAEIEERIGQ PMGCAESARL GRARRIGDAA GRYIEFCKSS FPNELDLRGL 190 200 210 220 230 240 RIALDCAHGA AYHIAPNVFH ELGAEVISVG VDPNGLNIND GVGATRPENL RQAVLSHGAD 250 260 270 280 290 300 LGIALDGDGD RLIMVDRQGE IYDGDKLLYV IASARAAEGR LDGVVGTLMS NLGFEHALER 310 320 330 340 350 360 RGVAFARAKV GDRYVLEMLH ERGWKIGGEN SGHIICLDCH TTGDGIISAL QVLAALKHRE 370 380 390 400 410 420 MSLSEACKDL VFYPQRLINV RLPAGFDWKA DARIAQTAAD AERTLGDTGR VLLRPSGTEP 430 440 450 LLRVMVEGRD EQLVESLARG IAGAVELAVA G

References

[1]

"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72." Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. , Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A. Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM406670 Genomic DNA. Translation: CAL94006.1.
RefSeq	YP_932893.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1K5A1.
Genome annotation databases
GeneID	4608823.
GenomeReviews	Gene locus azo1389 in contig AM406670_GR.
KEGG	azo:azo1389.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	STHPEAM.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_AZOSB

Accession

Primary (citable) accession number: A1K5A1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)