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A1K4Q0 (A1K4Q0_AZOSB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654
Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654
Gene names
Name:pqqC HAMAP MF_00654 EMBL CAL93805.1
Ordered Locus Names:azo1188
OrganismAzoarcus sp. (strain BH72) [Complete proteome] [HAMAP]
Taxonomic identifier62928 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
   Biological processPQQ biosynthesis HAMAP MF_00654
   Molecular functionOxidoreductase HAMAP MF_00654
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A1K4Q0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 5A01B4D8CB5DEFFC

FASTA26330,060
        10         20         30         40         50         60 
MEAELLAAPA ARTLAPNAGT HDRPPMSREE FEAQLRAKGT SYHIYHPFHV MMAEGRLTPA 

        70         80         90        100        110        120 
QLRGWVANRF YYQIAIPVKD AAIMSNCPDR EIRREWIQRI LDHDGYEIGG VSDPGGIEAW 

       130        140        150        160        170        180 
IRLGEAVGLS RDDVTSLRFV APAARFAVDA YINFARQRPW EEAVASSLTE LFAPHIHQQR 

       190        200        210        220        230        240 
IDTWPQVYPW VKTEGLQYFR NRLTQARRDV AHGLRFTLEH FSQTRALQER ALEILQFKLD 

       250        260 
VLWALADAIM LSQCEIEIKG PKA

« Hide

References

[1]"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72."
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. expand/collapse author list , Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.
Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM406670 Genomic DNA. Translation: CAL93805.1.
RefSeqYP_932692.1. NC_008702.1.

3D structure databases

ProteinModelPortalA1K4Q0.
SMRA1K4Q0. Positions 26-252.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1K4Q0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4609618.
GenomeReviewsGene locus azo1188 in contig AM406670_GR.
KEGGazo:azo1188.
PATRIC21010710. VBIAzoSp26047_1209.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG5424.
HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1K4Q0_AZOSB
AccessionPrimary (citable) accession number: A1K4Q0
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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