ID   A1K4P0_AZOSB            Unreviewed;       573 AA.
AC   A1K4P0;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=azo1178 {ECO:0000313|EMBL:CAL93795.1};
OS   Azoarcus sp. (strain BH72).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC   Azoarcus.
OX   NCBI_TaxID=418699 {ECO:0000313|EMBL:CAL93795.1, ECO:0000313|Proteomes:UP000002588};
RN   [1] {ECO:0000313|EMBL:CAL93795.1, ECO:0000313|Proteomes:UP000002588}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BH72 {ECO:0000313|EMBL:CAL93795.1,
RC   ECO:0000313|Proteomes:UP000002588};
RX   PubMed=17057704; DOI=10.1038/nbt1243;
RA   Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J.,
RA   Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C.,
RA   Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J.,
RA   Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
RT   "Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp.
RT   strain BH72.";
RL   Nat. Biotechnol. 24:1385-1391(2006).
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DR   EMBL; AM406670; CAL93795.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1K4P0; -.
DR   SMR; A1K4P0; -.
DR   STRING; 62928.azo1178; -.
DR   KEGG; azo:azo1178; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG0631; Bacteria.
DR   HOGENOM; CLU_034273_0_0_4; -.
DR   Proteomes; UP000002588; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   InterPro; IPR020635; Tyr_kinase_cat_dom.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF32; SERINE_THREONINE-PROTEIN KINASE PKAB; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SMART; SM00219; TyrKc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51746; PPM_2; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CAL93795.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002588};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:CAL93795.1};
KW   Transferase {ECO:0000313|EMBL:CAL93795.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        548..568
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..233
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   DOMAIN          266..527
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   573 AA;  62814 MW;  A4CACA15A018204C CRC64;
     MSVGQHSLAG AHDTNQDFHG AVLPGGHLLA AKGIALALAD GISSSSVSHL ASQTAVGSFL
     EDYYATSEAW TVRRAAQRVL GATNAWLHGQ TQRGEGRFDK DRGYVCTFSA LVLKGRDLHL
     LHVGDSRIYR LHPQSLEQLT EDHRVRHSSV ESYLARALGT GPHVEIDYRS WEAEAGEIYV
     LATDGAYAQL DAAAIHRAIA HHADDLDAAA AALVAQARAA GSDDDATLQL LRIDELPQDD
     APQAQLRREG LALPPALTPR SEFEGFTIVR ELQVSARSHV LLATDKDSGR PVVLKAPSVD
     LRGDAAYLDS FVLEEWVARR VDSPHVIKAW PGERRRRHLY VAMEYIEGQT LAQWMTDHPA
     PPLEAVRAIV EQLAQGVQAL HGRDMLHRDL RPENVMIDRD GTVKLIDLAN VHVAGLAEGR
     GGAEQGAPPG TLQYMAPECL LGQPASTAAD LFSLAAITYQ MLCGQLPYGL SVTRVRTQQD
     LRNLRYVPLR HHRPDLPAWL DGVLAKALQV APAKRQEAVS EFVHDLRTPG ARFQRAQRTP
     LVERDPVLFW KCLSAVLGAL VVGLLFYIRW RLA
//