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A1K498 (AROC_AZOSB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:azo1036
OrganismAzoarcus sp. (strain BH72) [Complete proteome] [HAMAP]
Taxonomic identifier62928 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 378378Chorismate synthase HAMAP MF_00300
PRO_1000022458

Sequences

Sequence LengthMass (Da)Tools
A1K498 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 06E8BC582109C99C

FASTA37840,254
        10         20         30         40         50         60 
MSGNTLGTLF CVTSFGESHG PAIGCVIDGC PPGLSLTAAD IQGELDRRKP GTSRHVTQRR 

        70         80         90        100        110        120 
EPDEVEILSG VFEGVTTGTP IALLIRNQDQ RSKDYGNIAE TFRPGHADYP YWQKYGIRDY 

       130        140        150        160        170        180 
RGGGRSSARE TAVRVAAGAV ARKWLSERYG IVIRGYMAQL GPLPIPFVSW DAVGDNPFFA 

       190        200        210        220        230        240 
PNAEIVPQLE SYMDELRKSG DSVGARINVV ASGVPVGWGE PVYDRLDADI AYAMMSINAV 

       250        260        270        280        290        300 
KGVEIGAGFA SVAQLGTEHG DELTPEGFLS NNAGGVLGGI SSGQDVLVSM AIKPTSSIRL 

       310        320        330        340        350        360 
DRRSIDREGN PVIVNTHGRH DPCVGIRATP VAEAMLALVL MDHALRHRAQ CGDVRTATPQ 

       370 
IAALAPEGVQ AVPSPRAE

« Hide

References

[1]"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72."
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. expand/collapse author list , Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.
Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BH72.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM406670 Genomic DNA. Translation: CAL93653.1.
RefSeqYP_932540.1. NC_008702.1.

3D structure databases

ProteinModelPortalA1K498.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1K498.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4609076.
GenomeReviewsGene locus azo1036 in contig AM406670_GR.
KEGGazo:azo1036.
PATRIC21010396. VBIAzoSp26047_1055.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMASRFTTQR.
PhylomeDBA1K498.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycASP62928:AZO1036-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_AZOSB
AccessionPrimary (citable) accession number: A1K498
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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