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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Azoarcus sp. (strain BH72)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei145UniRule annotation1
Active sitei578UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:azo0992
OrganismiAzoarcus sp. (strain BH72)
Taxonomic identifieri62928 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAzoarcus
Proteomesi
  • UP000002588 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000255481 – 917Phosphoenolpyruvate carboxylaseAdd BLAST917

Interactioni

Protein-protein interaction databases

STRINGi62928.azo0992.

Structurei

3D structure databases

SMRiA1K454.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
HOGENOMiHOG000238647.
KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A1K454-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPDKDAPLR EDIRLLGRLL GDTVRDQQGA ASFDLIERIR QTSVRFRRDE
60 70 80 90 100
DLAARRELED TLDALSREQT IQVVRAFSYF SHLANIAEDQ HHIRRSRAHL
110 120 130 140 150
LAGSAPREGS LAHAVGHALD EQRLDPTDLA AFFDTALISP VLTAHPTEVQ
160 170 180 190 200
RKSILNCQTV IARLLDERDR MQLTPDEAEA NLDALRRAVL TLWQTRMLRP
210 220 230 240 250
AKLSVIDEVN NGLSYFETTF LRELPRLYAA LEDRLAGAQP ALANHELPAF
260 270 280 290 300
LQVGSWIGGD RDGNPYVTAD VLEEALAMQA RVALDYYLDE LHTLGSQLSL
310 320 330 340 350
SQGLVGASDA LLALADRSPD QSPHRSDEPY RRAIAGIYAR LSATYRNLLG
360 370 380 390 400
HPPARHAVAE AEPYADVAAL ADDLDTLHRS LVANGTAALA RGRLRHLRRA
410 420 430 440 450
VRVFGFHLAP IDLRQNSDVH ERVVAELLEV ARPGAAYLAQ DEAGRCALLL
460 470 480 490 500
DELATARPLA SPHVRYSDDS EGELAIFRAA RRAHLRYGRG AIHNCIISKT
510 520 530 540 550
DDLSDLLELA VLLKEAGLLR PLEKALDVNI VPLFETIGDL ENAAGVMDRL
560 570 580 590 600
FSIPVYRELL AARDQTQEVM LGYSDSNKDG GFLTSGWALY KAEGELVEVF
610 620 630 640 650
GRHGVRLRLF HGRGGSVGRG GGPSYQAILA QPDGAVQGQI RLTEQGEVIA
660 670 680 690 700
AKYGNPEVGR RNLEVLVAAT LETSLRRDGG DATPRTFLDT MQALSDAAFT
710 720 730 740 750
CYRGLVYETP GFEQYFWEST VISEIAGLNI GSRPASRKKG TRIDDLRAIP
760 770 780 790 800
WVFSWSQCRL MLPGWFGFGS AVKQWLAAHP KDGLGLLQRM YREWSFFATL
810 820 830 840 850
LSNMDMVLSK TDLAIASRYA ELVKDPVLRD SIFERIRSEW KDTVDALLAI
860 870 880 890 900
TEQVELLDAN PLLKRSIRNR FPYLDPLNHV QVELLRRHRE GNGEDARIRN
910
GIHISINGIA AGLRNSG
Length:917
Mass (Da):101,775
Last modified:February 6, 2007 - v1
Checksum:i5786E67108799AA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406670 Genomic DNA. Translation: CAL93609.1.
RefSeqiWP_011764726.1. NC_008702.1.

Genome annotation databases

EnsemblBacteriaiCAL93609; CAL93609; azo0992.
KEGGiazo:azo0992.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCAPP_AZOSB
AccessioniPrimary (citable) accession number: A1K454
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: June 7, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families