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A1K3U6 (MURG_AZOSB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:azo0884
OrganismAzoarcus sp. (strain BH72) [Complete proteome] [HAMAP]
Taxonomic identifier62928 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 356356UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000002616

Sequences

Sequence LengthMass (Da)Tools
A1K3U6 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 6A3C5C2A27F171DA

FASTA35637,400
        10         20         30         40         50         60 
MKTLLVMAGG TGGHIFPGIA VAEALRAKGW RIVWMGNPDG MEARIVPSRG YDTAWVRFGA 

        70         80         90        100        110        120 
LRGKGLVRKL LLPVNLLVGF WQALGQLRRI KPDVVLGMGG YITFPGGMMA ALLGWPLVLH 

       130        140        150        160        170        180 
EQNSVAGLAN RVLAGVADRV LSGFPSVLKK AGWVGNPVRE DIASVAAPAA RFAGRSGPLN 

       190        200        210        220        230        240 
VLVVGGSLGA AVLNDTVPKA LARIPLEFRP QVVHQAGEKQ IDALRAAYAA AGVEGDLRPF 

       250        260        270        280        290        300 
IQDMAAAYAG ADLVICRAGA LTVAELAAVG VASLLVPFPH AVDDHQTGNA RFLAEHGGAY 

       310        320        330        340        350 
LLPQNELDAE RLAGILASLD RPQLLQMAEH ARAQAKPRAT EAVARACEEL AEGRKA

« Hide

References

[1]"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72."
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. expand/collapse author list , Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.
Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BH72.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM406670 Genomic DNA. Translation: CAL93501.1.
RefSeqYP_932388.1. NC_008702.1.

3D structure databases

ProteinModelPortalA1K3U6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1K3U6.

Protein family/group databases

CAZyGT28. Glycosyltransferase Family 28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4608840.
GenomeReviewsGene locus azo0884 in contig AM406670_GR.
KEGGazo:azo0884.
PATRIC21010064. VBIAzoSp26047_0900.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0707.
HOGENOMHBG617076.
OMAEDHQTKN.
PhylomeDBA1K3U6.
ProtClustDBPRK00726.

Enzyme and pathway databases

BioCycASP62928:AZO0884-MONOMER.

Family and domain databases

HAMAPMF_00033. MurG.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
KOK02563.
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. MurG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_AZOSB
AccessionPrimary (citable) accession number: A1K3U6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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