Reviewed,
UniProtKB/Swiss-Prot A1K3U3 (MRAY_AZOSB)
Last modified
February 9, 2010.
Version 31.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Phospho-N-acetylmuramoyl-pentapeptide-transferase EC=2.7.8.13 Alternative name(s): UDP-MurNAc-pentapeptide phosphotransferase | ||||
| Gene names |
| ||||
| Organism | Azoarcus sp. (strain BH72) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 62928 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus |
Protein attributes
| Sequence length | 362 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP MF_00038 |
| Catalytic activity | UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00038 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00038 |
| Subcellular location | Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_00038. |
| Sequence similarities | Belongs to the glycosyltransferase 4 family. MraY subfamily. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 362 | 362 | Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP MF_00038 | PRO_1000002936 | |||||
Regions | |||||||||
| Transmembrane | 18 – 38 | 21 | Potential | ||||||
| Transmembrane | 73 – 93 | 21 | Potential | ||||||
| Transmembrane | 97 – 117 | 21 | Potential | ||||||
| Transmembrane | 134 – 154 | 21 | Potential | ||||||
| Transmembrane | 160 – 180 | 21 | Potential | ||||||
| Transmembrane | 200 – 220 | 21 | Potential | ||||||
| Transmembrane | 237 – 257 | 21 | Potential | ||||||
| Transmembrane | 264 – 284 | 21 | Potential | ||||||
| Transmembrane | 289 – 309 | 21 | Potential | ||||||
| Transmembrane | 339 – 359 | 21 | Potential | ||||||
Sequences
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References
| [1] | "Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72." Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. Goesmann A.Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AM406670 Genomic DNA. Translation: CAL93498.1. |
| RefSeq | YP_932385.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A1K3U3. |
Genome annotation databases | |
| GeneID | 4609292. |
| GenomeReviews | Gene locus azo0881 in contig AM406670_GR. |
| KEGG | azo:azo0881. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0472. |
| HOGENOM | HBG708263. |
| OMA | HHHFEQK. |
| PhylomeDB | A1K3U3. |
Family and domain databases | |
| HAMAP | MF_00038. MraY. [Tree] |
| InterPro | IPR000715. Glycosyl_transferase_4. IPR018481. Glycosyl_Trfase_4_cons-reg. IPR003524. PNAcMuramoyl-5peptid_Trfase. IPR018480. PNAcMuramoyl-5peptid_Trfase_CS. [Graphical view] |
| PANTHER | PTHR22926. Glyco_trans_4. 1 hit. PTHR22926:SF3. PNAcPpept_trans. 1 hit. |
| Pfam | PF00953. Glycos_transf_4. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00445. mraY. 1 hit. |
| PROSITE | PS01347. MRAY_1. 1 hit. PS01348. MRAY_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MRAY_AZOSB | ||||||||
| Accession | Primary (citable) accession number: A1K3U3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


