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A1K2P0 (UBIC_AZOSB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable chorismate--pyruvate lyase
Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:azo0478
OrganismAzoarcus sp. (strain BH72) [Complete proteome] [HAMAP]
Taxonomic identifier62928 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Azoarcus

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Probable chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000292062

Sites

Binding site741Substrate By similarity
Binding site1131Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A1K2P0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: B199A525BAF103A5

FASTA18921,043
        10         20         30         40         50         60 
MQHPASGESW LARPPRTAER RLRPWLTDPA SLTARIRMRC GMFGVRVLRQ SAGALTPDER 

        70         80         90        100        110        120 
RLLGLRAGER ALLREVLLIA DGRPVVFARS VLAQREQRGG WLRLWRGIGS RPLGAALFSD 

       130        140        150        160        170        180 
PRIRRQPLAC ARIGAADARY HLARRALAGA ATLPPALWAR RSVFRLHGRS LLVSEFFLPA 


ILGLPDDPL

« Hide

References

[1]"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72."
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S. expand/collapse author list , Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.
Nat. Biotechnol. 24:1385-1391(2006) [PubMed: 17057704] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BH72.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM406670 Genomic DNA. Translation: CAL93095.1.
RefSeqYP_931982.1. NC_008702.1.

3D structure databases

ProteinModelPortalA1K2P0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1K2P0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4609706.
GenomeReviewsGene locus azo0478 in contig AM406670_GR.
KEGGazo:azo0478.
PATRIC21009212. VBIAzoSp26047_0482.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG120169.
HOGENOMHBG644467.
OMATREAVDC.
ProtClustDBCLSK766526.

Enzyme and pathway databases

BioCycASP62928:AZO0478-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_AZOSB
AccessionPrimary (citable) accession number: A1K2P0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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