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Protein

Virulence regulon transcriptional activator VirF

Gene

virF

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcriptional activator of the Yersinia virulence regulon.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi183 – 202H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation, Virulence

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Virulence regulon transcriptional activator VirF
Gene namesi
Name:virF
Ordered Locus Names:YEP0035
Encoded oniPlasmid pYVe80810 Publication
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Plasmid pYVe8081

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002858291 – 271Virulence regulon transcriptional activator VirFAdd BLAST271

Structurei

3D structure databases

ProteinModelPortaliA1JU91.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000247159.
OMAiEHAVIVV.
OrthoDBiPOG091H039M.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR014710. RmlC-like_jellyroll.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51215. SSF51215. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1JU91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLEIIKLE WATPIFKVVE HSQDGLYILL QGQVSWQNSS QTYDLDEGNM
60 70 80 90 100
LFLRRGSYAV RCGTKEPCQL LWIPLPGSFL STFLHRFGSL LSEIRRDNST
110 120 130 140 150
PKPLLIFNIS PILSQSIQNL CAILERSDFP SVLTQLRIEE LLLLLAFSSQ
160 170 180 190 200
GTLFLSALRH LGNRPEERLQ KFMEENYLQG WKLSKFAREF GMGLTTFKEL
210 220 230 240 250
FGTVYGISPR AWISERRILY AHQLLLNCKM SIVDIAMEAG FSSQSYFTQS
260 270
YRRRFGCTPS QARLTKIATT G
Length:271
Mass (Da):30,993
Last modified:February 6, 2007 - v1
Checksum:i6E8FD317446370DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF336309 Genomic DNA. Translation: AAK69232.1.
AM286416 Genomic DNA. Translation: CAL10057.1.
RefSeqiNP_783684.1. NC_004564.1.
NP_863532.1. NC_005017.1.
WP_005176447.1. NC_008791.1.
YP_001004087.1. NC_008791.1.

Genome annotation databases

EnsemblBacteriaiCAL10057; CAL10057; YEP0035.
GeneIDi1239218.
1449476.
4711913.
KEGGiyen:YEP0035.
PATRICi18559222. VBIYerEnt11519_0036.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF336309 Genomic DNA. Translation: AAK69232.1.
AM286416 Genomic DNA. Translation: CAL10057.1.
RefSeqiNP_783684.1. NC_004564.1.
NP_863532.1. NC_005017.1.
WP_005176447.1. NC_008791.1.
YP_001004087.1. NC_008791.1.

3D structure databases

ProteinModelPortaliA1JU91.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL10057; CAL10057; YEP0035.
GeneIDi1239218.
1449476.
4711913.
KEGGiyen:YEP0035.
PATRICi18559222. VBIYerEnt11519_0036.

Phylogenomic databases

HOGENOMiHOG000247159.
OMAiEHAVIVV.
OrthoDBiPOG091H039M.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR014710. RmlC-like_jellyroll.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51215. SSF51215. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVIRF_YERE8
AccessioniPrimary (citable) accession number: A1JU91
Secondary accession number(s): P13225, Q93KT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: February 6, 2007
Last modified: November 30, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.