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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:YE2849
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 335335Ribosomal RNA large subunit methyltransferase FPRO_0000349980Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi393305.YE2849.

Structurei

3D structure databases

ProteinModelPortaliA1JU40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A1JU40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSYAPENAY QRLSTMENKK VFPKEKSGLH PRNRHRSRYD FDALSVSCPE
60 70 80 90 100
LIPFLAPTAY GDISIDFASP LAVKMLNKAL LKHFYGIEYW DIPADFLCPP
110 120 130 140 150
IPGRADYVHH LADLLASCND GVIPQGKNVA VLDIGVGANC IYPIIGQREY
160 170 180 190 200
GWRFTGTDID PQALSAAKMV VSMNPTLKNT LRLKQQKNPQ AIFDGILAVN
210 220 230 240 250
ERYDATLCNP PFHGSAEEAA ATTRRKLHKL GKSEVAAKPV QNFGGKNSEL
260 270 280 290 300
WCEGGEEGFV SRMVAESATK AQNCFWFTSL ISKKTTLPAI YHALRYANAV
310 320 330
EVRTIDMAQG QKVSRFVAWT FLTPEQQAAW KAERW
Length:335
Mass (Da):37,371
Last modified:February 6, 2007 - v1
Checksum:i93B712403F686CDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL12883.1.
RefSeqiWP_011816763.1. NC_008800.1.
YP_001007038.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL12883; CAL12883; YE2849.
GeneIDi4714303.
KEGGiyen:YE2849.
PATRICi18565347. VBIYerEnt11519_3027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL12883.1.
RefSeqiWP_011816763.1. NC_008800.1.
YP_001007038.1. NC_008800.1.

3D structure databases

ProteinModelPortaliA1JU40.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE2849.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL12883; CAL12883; YE2849.
GeneIDi4714303.
KEGGiyen:YE2849.
PATRICi18565347. VBIYerEnt11519_3027.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 13174 / 8081.

Entry informationi

Entry nameiRLMF_YERE8
AccessioniPrimary (citable) accession number: A1JU40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: February 6, 2007
Last modified: November 11, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.