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A1JSN4 (DCYD_YERE8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-cysteine desulfhydrase
EC=4.4.1.15
Gene names
Name:dcyD
Ordered Locus Names:YE2517
OrganismYersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [Complete proteome] [HAMAP]
Taxonomic identifier393305 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia ›

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine By similarity. HAMAP-Rule MF_01045

Catalytic activity

D-cysteine + H2O = H2S + NH3 + pyruvate. HAMAP-Rule MF_01045

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-amino acid metabolic process

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionD-cysteine desulfhydrase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330D-cysteine desulfhydrase HAMAP-Rule MF_01045
PRO_1000064269

Amino acid modifications

Modified residue521N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A1JSN4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 6510478456C33701

FASTA33035,196
        10         20         30         40         50         60 
MTLQHKLAQF PRLDLVGNAT PLEKLSRLSD YLGREIYIKR DDVTPLALGG NKLRKLEFLA 

        70         80         90        100        110        120 
ADALRQGADT LVTAGAIQSN HVRQTAAVAA KLGLHCVALL ENPIGTSQEN YLTNGNRLLL 

       130        140        150        160        170        180 
DLFNVEVVMC DGLHDPNQQL AELATRIEAQ GFRPYVVPVG GSNAFGALGY VQCALEIAAQ 

       190        200        210        220        230        240 
SAGNVTFSSV VVASGSAGTH AGLAVGLQQL LPQTELIGVT VSRKAEEQRP KVIHIQQELA 

       250        260        270        280        290        300 
TSLGVTSGPA DITLWDDYFA PQYGMPNEEG LAAIGLLARL EGILLDPVYT GKAMAGLLDG 

       310        320        330 
LEQKKFRDDG PILFIHTGGA PALFAYHPQV

« Hide

References

[1]"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081."
Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S. expand/collapse author list , Quail M.A., Dougan G., Parkhill J., Prentice M.B.
PLoS Genet. 2:2039-2051(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8081.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM286415 Genomic DNA. Translation: CAL12560.1.
RefSeqYP_001006724.1. NC_008800.1.

3D structure databases

ProteinModelPortalA1JSN4.
ModBaseSearch...

Protein-protein interaction databases

STRING393305.YE2517.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4712833.
KEGGyen:YE2517.
PATRIC18564628. VBIYerEnt11519_2671.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2515.
HOGENOMHOG000022460.
KOK05396.
OMAPYLVPIG.
ProtClustDBPRK03910.

Family and domain databases

HAMAPMF_01045. D-Cys_desulfhydr.
InterProIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR023702. D_Cys_desulphydr_bac.
IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
[Graphical view]
PfamPF00291. PALP. 1 hit.
[Graphical view]
PIRSFPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMSSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMsTIGR01275. ACC_deam_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCYD_YERE8
AccessionPrimary (citable) accession number: A1JSN4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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