Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional regulator MalT

Gene

malT

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box): 5'-GGA[TG]GA-3'.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi39 – 46ATPUniRule annotation8
DNA bindingi856 – 875H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Carbohydrate metabolism, Transcription, Transcription regulation

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator MalTUniRule annotation
Alternative name(s):
ATP-dependent transcriptional activator MalTUniRule annotation
Gene namesi
Name:malTUniRule annotation
Ordered Locus Names:YE3990
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000857831 – 903HTH-type transcriptional regulator MalTAdd BLAST903

Proteomic databases

PRIDEiA1JSF2.

Interactioni

Subunit structurei

Monomer in solution but oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.UniRule annotation

Protein-protein interaction databases

STRINGi393305.YE3990.

Structurei

3D structure databases

ProteinModelPortaliA1JSF2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini832 – 897HTH luxR-typeUniRule annotationAdd BLAST66

Sequence similaritiesi

Contains 1 HTH luxR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG41061ZR. Bacteria.
COG2909. LUCA.
HOGENOMiHOG000218261.
KOiK03556.
OMAiSDWVSNA.
OrthoDBiPOG091H0FN0.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01247. HTH_type_MalT. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR011990. TPR-like_helical_dom.
IPR023768. Tscrpt_reg_HTH_MalT.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF48452. SSF48452. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1JSF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIPSKLSRP VRLQNTVIRD RLLVKLSGVA NYRLTLINCP AGYGKTTLIA
60 70 80 90 100
QWAADQSDLG WYSLDESDNQ PERFATYLVA AIQLATGGHC SKSEAISQKH
110 120 130 140 150
QYASLSALFA QLFIELSEWD GPLYLVIDDY HLITNDAIHE AMRFFLRHQP
160 170 180 190 200
ENLTLIMLSR TLPPLGIANL RVRDQLLELG MQQLAFNHQE AQQFFDCRLS
210 220 230 240 250
VPLEQGDSSR LCDEVEGWAT ALQLIALSSR QPNSSAQKSA KRLAGLNASH
260 270 280 290 300
LSDYLVDEVL DQVDSDARAF LLRCSVLRSM NDALIVRLTG EDNGQQRLEE
310 320 330 340 350
LERQGLFIHR MDDSGEWFCF HPLFATFLRQ RCQWEMALEL PELHHAAAEG
360 370 380 390 400
WMALGYPAEA IHHALAAGDV GMLRDILLQH AWTLFNHSEL ALLEQCLVAL
410 420 430 440 450
PYSLLVQNPE LALLQAWLAQ SQHRYGEVNT LLERAESAMQ ERKIPIDEIL
460 470 480 490 500
RAEFDALRAQ VAINAGKPEE AEKLATDALK YLPMANFYSR IVATSVTGEV
510 520 530 540 550
HHCKGELSRA LPMMQQTEQM ARRHEAYHYA LWALLQQSEI LIAQGFLQAA
560 570 580 590 600
YETQDKAFDL IHEQHLEQLP MHEFLLRIRS QVLWSWSRLD EAEEAARKGI
610 620 630 640 650
EILVNYQPQQ QLQCLAMLAK CSLARGDLDN ANMYIQRCEA LQHGSQYHLD
660 670 680 690 700
WITNADKPRV IHWQMTGDKA AAANWLRQAE KPGMADNHFL QGQWRNIARI
710 720 730 740 750
QIMLGRFNEA EVVLDELNEN ARRLRLTSDL NRNLLLSNIL YWQTERKSEA
760 770 780 790 800
QKALIESLSL ANRTGFISHF VIEGEVMAQQ LRQLIQLNAL PELEQHRAQR
810 820 830 840 850
ILKDINQHHR HKFAHFDEIF VDKLLTHPQV PELIRTSPLT QREWQVLGLI
860 870 880 890 900
YSGYSNDQIA GELEVAATTI KTHIRNLYQK LGVAHRQDAV QQAQRLLQMM

GYV
Length:903
Mass (Da):103,209
Last modified:February 6, 2007 - v1
Checksum:iBFFE9677F9E7D450
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL14010.1.
RefSeqiWP_011817355.1. NC_008800.1.
YP_001008136.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL14010; CAL14010; YE3990.
GeneIDi4716203.
KEGGiyen:YE3990.
PATRICi18567846. VBIYerEnt11519_4248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL14010.1.
RefSeqiWP_011817355.1. NC_008800.1.
YP_001008136.1. NC_008800.1.

3D structure databases

ProteinModelPortaliA1JSF2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE3990.

Proteomic databases

PRIDEiA1JSF2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL14010; CAL14010; YE3990.
GeneIDi4716203.
KEGGiyen:YE3990.
PATRICi18567846. VBIYerEnt11519_4248.

Phylogenomic databases

eggNOGiENOG41061ZR. Bacteria.
COG2909. LUCA.
HOGENOMiHOG000218261.
KOiK03556.
OMAiSDWVSNA.
OrthoDBiPOG091H0FN0.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01247. HTH_type_MalT. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR011990. TPR-like_helical_dom.
IPR023768. Tscrpt_reg_HTH_MalT.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF48452. SSF48452. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMALT_YERE8
AccessioniPrimary (citable) accession number: A1JSF2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.