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A1JS36 (A1JS36_YERE8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174 EMBL CAL12510.1
Ordered Locus Names:YE2467
OrganismYersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [Complete proteome] [HAMAP]
Taxonomic identifier393305 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174 SAAS SAAS017649

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174 SAAS SAAS017649

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174 SAAS SAAS017649

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding218 – 2236NAD By similarity HAMAP MF_01174

Sites

Active site2411 By similarity HAMAP MF_01174
Active site2751 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
A1JS36 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: C6C90C6A3D224322

FASTA48852,549
        10         20         30         40         50         60 
MFIQGEWRTG KGAHFDKHDP MEQQLLWQAR AADSADVAAA CRAARDAFPT WARTPLEQRV 

        70         80         90        100        110        120 
AIIQRFAVLL EQHKQQLART ISLETSKPHW ETLTEVQAMM GKVAISLQAY QTRTGSSQTP 

       130        140        150        160        170        180 
MTDAISVLRH RPHGVLAVFG PYNFPGHLPN GHIVPALLAG NTVVFKPSEL TPVTAEETVK 

       190        200        210        220        230        240 
LWQLAGIPDG VLNLVQGGRD TGEALAAQPD IDGLLFTGSA NTGYHLHRQL AGQPEKILAL 

       250        260        270        280        290        300 
EMGGNNALIV EQVKDCDAAV NLAIQSAFIS AGQRCTCSRR LLVKSGAEGD AFLQRFVAVS 

       310        320        330        340        350        360 
KALRIGRWDS QPAPFMGAVI SSQAAEKMLA AQQHLLSLGG KALLTMTRPD SQSAVLTPSI 

       370        380        390        400        410        420 
IDITGISEVP DEEYFGPLVS VIRYSDFNQA LKIANQTRFG LAIGLVSEDR QQFEQLLLEA 

       430        440        450        460        470        480 
RAGIVNWNKP LTGASSAAPF GGVGASGNHR PSAFYAADYC AWPMASLESE SLTLPATLSP 


GISFDLPD

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References

[1]"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081."
Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S. expand/collapse author list , Quail M.A., Dougan G., Parkhill J., Prentice M.B.
PLoS Genet. 2:2039-2051(2006) [PubMed: 17173484] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM286415 Genomic DNA. Translation: CAL12510.1.
RefSeqYP_001006674.1. NC_008800.1.

3D structure databases

ProteinModelPortalA1JS36.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1JS36.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4712505.
GenomeReviewsGene locus YE2467 in contig AM286415_GR.
KEGGyen:YE2467.
NMPDRfig|630.2.peg.2390.
PATRIC18564522. VBIYerEnt11519_2618.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAMTQRDPR.
PhylomeDBA1JS36.
ProtClustDBPRK09457.

Enzyme and pathway databases

BioCycYENT393305:YE2467-MONOMER.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1JS36_YERE8
AccessionPrimary (citable) accession number: A1JS36
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info