ID   ASTE_YERE8              Reviewed;         330 AA.
AC   A1JS32;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Succinylglutamate desuccinylase;
DE            EC=3.5.1.96;
GN   Name=astE; OrderedLocusNames=YE2465;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the
RT   high pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Transforms N(2)-succinylglutamate into succinate and
CC       glutamate (By similarity).
CC   -!- CATALYTIC ACTIVITY: N-succinyl-L-glutamate + H(2)O = succinate +
CC       L-glutamate.
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- PATHWAY: Amino-acid degradation; L-arginine degradation via AST
CC       pathway; L-glutamate and succinate from L-arginine: step 5/5.
CC   -!- SIMILARITY: Belongs to the aspA/astE family. Succinylglutamate
CC       desuccinylase subfamily.
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DR   EMBL; AM286415; CAL12508.1; -; Genomic_DNA.
DR   RefSeq; YP_001006672.1; -.
DR   GeneID; 4712503; -.
DR   GenomeReviews; AM286415_GR; YE2465.
DR   KEGG; yen:YE2465; -.
DR   NMPDR; fig|630.2.peg.2388; -.
DR   OMA; A1JS32; EKFAIYP.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:HAMAP.
DR   GO; GO:0009017; F:succinylglutamate desuccinylase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019544; P:arginine catabolic process to glutamate; IEA:HAMAP.
DR   HAMAP; MF_00767; -; 1.
DR   InterPro; IPR007036; Aste_AspA.
DR   InterPro; IPR016681; SuccinylGlu_desuccinylase.
DR   Pfam; PF04952; AstE_AspA; 1.
DR   PIRSF; PIRSF017020; AstE; 1.
DR   TIGRFAMs; TIGR03242; arg_catab_astE; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; Complete proteome; Hydrolase; Metal-binding;
KW   Zinc.
FT   CHAIN         1    330       Succinylglutamate desuccinylase.
FT                                /FTId=PRO_1000017334.
FT   ACT_SITE    210    210       Potential.
FT   METAL        53     53       Zinc (By similarity).
FT   METAL        56     56       Zinc (By similarity).
FT   METAL       147    147       Zinc (By similarity).
SQ   SEQUENCE   330 AA;  36775 MW;  B86527782F6E931B CRC64;
     MPDFLSITLS GVPPSLTSGE TSNLKWQWVD EGVLMLTPHG ACSQSVVLSA GIHGNETAPI
     EILNQLVSDL LASQLPLAVR LLVILGNPPA IRAGERYLTA DINRMFGGRY KNHSLTDEAR
     RAEILEQKVG EFFASDPLSL RLHYDLHTAI RGSHHNRFGL LPYRTTPYCA AMLRWLKDSE
     LDALVMHTSA GGTFAHFSSE FCQAASCTLE LGKALPFGQN QLEQFRPITA GLRALVSGGQ
     LPTRSTEAMI FYRVVKSLLK QHADFKLWVA DDTVNFTRYP QGTLMIEQLN EHYCVEHEYE
     WILFPNPRVA LGLRAGIMLV QMDENDLLQA
//