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Protein

Putative phosphoenolpyruvate synthase regulatory protein

Gene

YE2177

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

Catalytic activityi

ADP + [pyruvate, water dikinase] = AMP + [pyruvate, water dikinase] phosphate.UniRule annotation
[Pyruvate, water dikinase] phosphate + phosphate = [pyruvate, water dikinase] + diphosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi153 – 160ADPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphoenolpyruvate synthase regulatory proteinUniRule annotation (EC:2.7.11.33UniRule annotation, EC:2.7.4.28UniRule annotation)
Short name:
PEP synthase regulatory proteinUniRule annotation
Short name:
PSRPUniRule annotation
Alternative name(s):
Pyruvate, water dikinase regulatory proteinUniRule annotation
Gene namesi
Ordered Locus Names:YE2177
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003167571 – 273Putative phosphoenolpyruvate synthase regulatory proteinAdd BLAST273

Interactioni

Protein-protein interaction databases

STRINGi393305.YE2177.

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218053.
KOiK09773.
OMAiYAQCEFE.
OrthoDBiPOG091H00ZQ.

Family and domain databases

HAMAPiMF_01062. PSRP. 1 hit.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026530. PSRP.
IPR008917. TF_DNA-bd.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
SUPFAMiSSF47454. SSF47454. 1 hit.

Sequencei

Sequence statusi: Complete.

A1JPI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERSVFYISD GTAITAEVLG HAVLSQFPVK ATTFTLPFVE SATRAQEVCE
60 70 80 90 100
KINEIYRETG VRPLVFYSII SPEVRELIQH SEGFCQDIVQ ALVAPLQGEL
110 120 130 140 150
GVSPQPVLNR THGLTESNLG KYDARIAAID YALAHDDGIS LRNLDQAQVI
160 170 180 190 200
LLGVSRCGKT PTSLYLAMQF GIRAANYPFI ADDMDNLQLP AALKPFQHKL
210 220 230 240 250
FGLTINPERL AAIREERREN SRYASLRQCR MEVGEVEALF RKNQIRYLNS
260 270
TNYSVEEIST KILDILGMSR RMF
Length:273
Mass (Da):30,672
Last modified:February 6, 2007 - v1
Checksum:i0005E00B01B51D12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL12247.1.
RefSeqiWP_005169416.1. NC_008800.1.
YP_001006417.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL12247; CAL12247; YE2177.
GeneIDi4713500.
KEGGiyen:YE2177.
PATRICi18563964. VBIYerEnt11519_2342.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL12247.1.
RefSeqiWP_005169416.1. NC_008800.1.
YP_001006417.1. NC_008800.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE2177.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL12247; CAL12247; YE2177.
GeneIDi4713500.
KEGGiyen:YE2177.
PATRICi18563964. VBIYerEnt11519_2342.

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218053.
KOiK09773.
OMAiYAQCEFE.
OrthoDBiPOG091H00ZQ.

Family and domain databases

HAMAPiMF_01062. PSRP. 1 hit.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026530. PSRP.
IPR008917. TF_DNA-bd.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
SUPFAMiSSF47454. SSF47454. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPSRP_YERE8
AccessioniPrimary (citable) accession number: A1JPI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.