A1JP85 (GLND_YERE8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	YE3286

Organism

Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [Complete proteome] [HAMAP]

Taxonomic identifier

393305 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia enterocolitica › Yersinia enterocolitica subsp. enterocolitica

Protein attributes

Sequence length	892 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 892	892	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000022356

Sequences

	Sequence		Length	Mass (Da)
	A1JP85 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: F9A01583B3D41D50	FASTA	892	103,044
	10 20 30 40 50 60 MSDNHTEHSV LPAVTKVIPE QPASPATYLD SELNCPELKQ RLETFQSWLA DAFNGGISAE 70 80 90 100 110 120 TLIAARSDYI DRLLGRLWTF YGFDDVPETA LVAVGGYGRG ELHPLSDIDV LILSKQRLND 130 140 150 160 170 180 EHAQRVGQLI TLLWDLKLEV GHSVRTLEEC LLEGLADLTV ATNMVESRLI CGDVALFLQM 190 200 210 220 230 240 QKHIFSDNFW PSPKFFHAKV VEQQERHKRY HGTSYNLEPD IKSSPGGLRD IHTLQWVARR 250 260 270 280 290 300 HFGATSLSEM VDFGFLTKAE RNELIESQSF LWRIRFALHL VLTRYDNRLL FDRQLSVAQL 310 320 330 340 350 360 LQYQGEGNEP VERMMKDFYR MTRRVSELNN MLLQLFDEAI LALDTNEKPR PLDDEFQLRG 370 380 390 400 410 420 DLIDLRDENL FVDKPEAIMR MFYLMVRNQD IKGIYSTTVR RLRHARRHLK QPLCNIPEAR 430 440 450 460 470 480 KLFMAILRHP GAVSRALLPM HRHSVLWAYM PQWGSIVGQM QFDLFHAYTV DEHTIRVLLK 490 500 510 520 530 540 LESFADESTR PRHPLCVELY PRLPQPELLL LAALFHDIAK GRGGDHSILG AHDVLEFAEQ 550 560 570 580 590 600 HGLNSREAQL VAWLVRCHLL MSVTAQRRDI QDPAVIQQFS AEVQSETRLR YLVSLTVADI 610 620 630 640 650 660 CATNENLWNS WKQSLLRELY FATEKQLRRG MQNSPDLRER VRHHRLQALA LLRMDNIDEE 670 680 690 700 710 720 ALHHIWSRCR ADYFLRHSPN QLAWHARHLL EHDSTKPLVL VSRQATRGGT EIFIWCPDRP 730 740 750 760 770 780 SLFAAVVGEL DRRNLSVHDA QIFTNRDGMA MDTFIVLEPD GSPLAQDRHP IIIHALQQAM 790 800 810 820 830 840 TRQNYQHPRV RRLSPKLRHF SVPTETNFLP THNERRTYLE LIALDQPGLL ARVGDIFADL 850 860 870 880 890 GLSLHSARIT TIGERVEDLF VLADKDRRAL SIETRRELAQ RLTDTLNPND KL

References

[1]

"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081." Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S. , Quail M.A., Dougan G., Parkhill J., Prentice M.B. PLoS Genet. 2:2039-2051(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 8081.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286415 Genomic DNA. Translation: CAL13316.1.
RefSeq	YP_001007460.1. NC_008800.1.
3D structure databases
ProteinModelPortal	A1JP85.
ModBase	Search...
Protein-protein interaction databases
STRING	393305.YE3286.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4713381.
KEGG	yen:YE3286.
PATRIC	18566317. VBIYerEnt11519_3496.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05007.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_YERE8

Accession

Primary (citable) accession number: A1JP85

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program