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A1JMP2

- PNCB_YERE8

UniProt

A1JMP2 - PNCB_YERE8

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:YE1565
    OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
    Taxonomic identifieri393305 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000642: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Nicotinate phosphoribosyltransferasePRO_1000025020Add
    BLAST

    Proteomic databases

    PRIDEiA1JMP2.

    Interactioni

    Protein-protein interaction databases

    STRINGi393305.YE1565.

    Structurei

    3D structure databases

    ProteinModelPortaliA1JMP2.
    SMRiA1JMP2. Positions 5-377.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    HOGENOMiHOG000284928.
    KOiK00763.
    OMAiQAVFHRY.
    OrthoDBiEOG6X10XB.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1JMP2-1 [UniParc]FASTAAdd to Basket

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    MTQDASPILT SLLDTDAYKL HMQQAVFHRY RHITVAAEFR CRGDELLGEY    50
    ADEIRHQITL MSQLALTDDE YQYLSGLPFF KNDYLNWLRA FRFNPEQVTV 100
    SDNDGELDIR ITGLWCETIL WEVPLLAVIS EIVHRRRSAH VTADLAVSQL 150
    RSKLQQFNAL SADIDITHFK LMDFGTRRRF SREIQHAIVS HLKDEFPYLV 200
    GTSNYDLARK LSLDPVGTQA HEWFQAHQQI SPVLANSQRV ALQAWLDEYP 250
    NQLGVALTDC ITMDAFLRDF DKTFADRYQG LRHDSGDPVE WGEKAIAHYE 300
    KLGIDPMSKT LVFSDNLDLE KALSLYRHFY QRVKLVFGIG TRLTCDIPGI 350
    KPLNIVIKLV ECNDKPVAKL SDSPGKTICH DPAFVDELRE AFALPLVKKA 400
    S 401
    Length:401
    Mass (Da):45,896
    Last modified:February 6, 2007 - v1
    Checksum:i23AA5E74D4E71483
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL11643.1.
    RefSeqiWP_011816044.1. NC_008800.1.
    YP_001005859.1. NC_008800.1.

    Genome annotation databases

    EnsemblBacteriaiCAL11643; CAL11643; YE1565.
    GeneIDi4713260.
    KEGGiyen:YE1565.
    PATRICi18562646. VBIYerEnt11519_1693.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL11643.1 .
    RefSeqi WP_011816044.1. NC_008800.1.
    YP_001005859.1. NC_008800.1.

    3D structure databases

    ProteinModelPortali A1JMP2.
    SMRi A1JMP2. Positions 5-377.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393305.YE1565.

    Proteomic databases

    PRIDEi A1JMP2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL11643 ; CAL11643 ; YE1565 .
    GeneIDi 4713260.
    KEGGi yen:YE1565.
    PATRICi 18562646. VBIYerEnt11519_1693.

    Phylogenomic databases

    eggNOGi COG1488.
    HOGENOMi HOG000284928.
    KOi K00763.
    OMAi QAVFHRY.
    OrthoDBi EOG6X10XB.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 13174 / 8081.

    Entry informationi

    Entry nameiPNCB_YERE8
    AccessioniPrimary (citable) accession number: A1JMP2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3