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A1JMP2 (PNCB_YERE8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:YE1565
OrganismYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) [Complete proteome] [HAMAP]
Taxonomic identifier393305 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000025020

Sequences

Sequence LengthMass (Da)Tools
A1JMP2 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 23AA5E74D4E71483

FASTA40145,896
        10         20         30         40         50         60 
MTQDASPILT SLLDTDAYKL HMQQAVFHRY RHITVAAEFR CRGDELLGEY ADEIRHQITL 

        70         80         90        100        110        120 
MSQLALTDDE YQYLSGLPFF KNDYLNWLRA FRFNPEQVTV SDNDGELDIR ITGLWCETIL 

       130        140        150        160        170        180 
WEVPLLAVIS EIVHRRRSAH VTADLAVSQL RSKLQQFNAL SADIDITHFK LMDFGTRRRF 

       190        200        210        220        230        240 
SREIQHAIVS HLKDEFPYLV GTSNYDLARK LSLDPVGTQA HEWFQAHQQI SPVLANSQRV 

       250        260        270        280        290        300 
ALQAWLDEYP NQLGVALTDC ITMDAFLRDF DKTFADRYQG LRHDSGDPVE WGEKAIAHYE 

       310        320        330        340        350        360 
KLGIDPMSKT LVFSDNLDLE KALSLYRHFY QRVKLVFGIG TRLTCDIPGI KPLNIVIKLV 

       370        380        390        400 
ECNDKPVAKL SDSPGKTICH DPAFVDELRE AFALPLVKKA S 

« Hide

References

[1]"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081."
Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S. expand/collapse author list , Quail M.A., Dougan G., Parkhill J., Prentice M.B.
PLoS Genet. 2:2039-2051(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 13174 / 8081.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM286415 Genomic DNA. Translation: CAL11643.1.
RefSeqYP_001005859.1. NC_008800.1.

3D structure databases

ProteinModelPortalA1JMP2.
SMRA1JMP2. Positions 5-377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING393305.YE1565.

Proteomic databases

PRIDEA1JMP2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL11643; CAL11643; YE1565.
GeneID4713260.
KEGGyen:YE1565.
PATRIC18562646. VBIYerEnt11519_1693.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_YERE8
AccessionPrimary (citable) accession number: A1JMP2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways