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A1JLL1

- NUON_YERE8

UniProt

A1JLL1 - NUON_YERE8

Protein

NADH-quinone oxidoreductase subunit N

Gene

nuoN

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

    Catalytic activityi

    NADH + quinone = NAD+ + quinol.UniRule annotation

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
    2. quinone binding Source: UniProtKB-KW

    GO - Biological processi

    1. ATP synthesis coupled electron transport Source: InterPro
    2. transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-quinone oxidoreductase subunit NUniRule annotation (EC:1.6.99.5UniRule annotation)
    Alternative name(s):
    NADH dehydrogenase I subunit NUniRule annotation
    NDH-1 subunit NUniRule annotation
    Gene namesi
    Name:nuoNUniRule annotation
    Ordered Locus Names:YE1356
    OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
    Taxonomic identifieri393305 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000642: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 485485NADH-quinone oxidoreductase subunit NPRO_1000017380Add
    BLAST

    Keywords - PTMi

    Quinone

    Interactioni

    Subunit structurei

    NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi393305.YE1356.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei10 – 3021HelicalUniRule annotationAdd
    BLAST
    Transmembranei35 – 5521HelicalUniRule annotationAdd
    BLAST
    Transmembranei75 – 9521HelicalUniRule annotationAdd
    BLAST
    Transmembranei104 – 12421HelicalUniRule annotationAdd
    BLAST
    Transmembranei125 – 14521HelicalUniRule annotationAdd
    BLAST
    Transmembranei159 – 17921HelicalUniRule annotationAdd
    BLAST
    Transmembranei203 – 22321HelicalUniRule annotationAdd
    BLAST
    Transmembranei235 – 25521HelicalUniRule annotationAdd
    BLAST
    Transmembranei271 – 29121HelicalUniRule annotationAdd
    BLAST
    Transmembranei297 – 31721HelicalUniRule annotationAdd
    BLAST
    Transmembranei327 – 34721HelicalUniRule annotationAdd
    BLAST
    Transmembranei374 – 39421HelicalUniRule annotationAdd
    BLAST
    Transmembranei408 – 42720HelicalUniRule annotationAdd
    BLAST
    Transmembranei449 – 46921HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I subunit 2 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1007.
    HOGENOMiHOG000100796.
    KOiK00343.
    OMAiSIVQLAM.
    OrthoDBiEOG64JFNZ.

    Family and domain databases

    HAMAPiMF_00445. NDH1_NuoN_1.
    InterProiIPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view]
    PfamiPF00361. Oxidored_q1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01770. NDH_I_N. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1JLL1-1 [UniParc]FASTAAdd to Basket

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    MTITPQQLQA MLPLLIVGLT VVVVMLSIAW RRDHFINATL TVIGLNLALL    50
    SLYFVGQVGP LDVTPLMRVD GYAMFYIGLV IVASLATSTF AYPWLNGYPD 100
    NREEFYLLVL IATMGGILLA SANHLASLFL GIELISLPLF GLIGYAYRQK 150
    RSLEASIKYM LLSAAASSFL LFGMALLYAE SGSLSFAGLG KSLSDSMIHQ 200
    PLILAGLGMM IVGLGFKLSL VPFQLWTPDV YQGAPAPVST FLATASKIAI 250
    FAVVMRLFLY APAADSEAVR LVLSLIAVAS ILFGNLMAIS QTNIKRLLGY 300
    SSIAHLGYLL IALVAVQTHQ LALETAGVYL AGYLFSSLGA FGVVSLMSSP 350
    YKGPDAESLF SYRGLFWHKP ILSAVMTVMM LSLAGIPMTL GFIGKFFVVA 400
    MGVSANLWWL TGAVVLGSAI GLYYYLRVTV SLYLSAPETL VRDTPSNWAL 450
    TAGGVVVLIS AILVLVLGIY PQPLISLVQL AQPLM 485
    Length:485
    Mass (Da):52,062
    Last modified:February 6, 2007 - v1
    Checksum:i90048C8FCB7B9F56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL11447.1.
    RefSeqiYP_001005672.1. NC_008800.1.

    Genome annotation databases

    EnsemblBacteriaiCAL11447; CAL11447; YE1356.
    GeneIDi4712724.
    KEGGiyen:YE1356.
    PATRICi18562204. VBIYerEnt11519_1475.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL11447.1 .
    RefSeqi YP_001005672.1. NC_008800.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393305.YE1356.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL11447 ; CAL11447 ; YE1356 .
    GeneIDi 4712724.
    KEGGi yen:YE1356.
    PATRICi 18562204. VBIYerEnt11519_1475.

    Phylogenomic databases

    eggNOGi COG1007.
    HOGENOMi HOG000100796.
    KOi K00343.
    OMAi SIVQLAM.
    OrthoDBi EOG64JFNZ.

    Family and domain databases

    HAMAPi MF_00445. NDH1_NuoN_1.
    InterProi IPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view ]
    Pfami PF00361. Oxidored_q1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01770. NDH_I_N. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 13174 / 8081.

    Entry informationi

    Entry nameiNUON_YERE8
    AccessioniPrimary (citable) accession number: A1JLL1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3