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Protein

5'-deoxynucleotidase YE1340

Gene

YE1340

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 2'-deoxyribonucleoside 5'-monophosphate + H2O = a 2'-deoxyribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei16Appears to be important in orienting the phosphate for catalysisUniRule annotation1
Metal bindingi31Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei31SubstrateUniRule annotation1
Metal bindingi66Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi67Divalent metal cationUniRule annotation1
Binding sitei67SubstrateUniRule annotation1
Metal bindingi135Divalent metal cationUniRule annotation1
Binding sitei135SubstrateUniRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-deoxynucleotidase YE1340UniRule annotation (EC:3.1.3.89UniRule annotation)
Alternative name(s):
5'-deoxyribonucleotidaseUniRule annotation
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:YE1340
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000649611 – 1975'-deoxynucleotidase YE1340Add BLAST197

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi393305.YE1340.

Structurei

3D structure databases

ProteinModelPortaliA1JLF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni16 – 17Substrate bindingUniRule annotation2
Regioni75 – 78Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the 5DNU family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DK2. Bacteria.
COG1896. LUCA.
HOGENOMiHOG000276964.
KOiK08722.
OMAiMPTPIKY.
OrthoDBiPOG091H00DC.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
HAMAPiMF_01100. 5DNU. 1 hit.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR022971. YfbR.
[Graphical view]
PfamiPF13023. HD_3. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1JLF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHFFAHLSR LKLINRWPLM RNVRTENVSE HSLQVAFVAH ALAIIKNRKF
60 70 80 90 100
NGNLNADRIA LLAMYHDASE VITGDLPTPI KYYNPQIAHE YKKIEKVAQQ
110 120 130 140 150
KLIEMLPEEL QHDFRCLLDE HYYSEEEKAL VKQADALCAY LKCLEELSAG
160 170 180 190
NNEFIQAKVR LEKTLAMRQS PEMDYFMEVF VPSFSLSLDE ISLDSLD
Length:197
Mass (Da):22,846
Last modified:February 6, 2007 - v1
Checksum:iD554209E575C20E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL11429.1.
RefSeqiWP_005171739.1. NC_008800.1.
YP_001005657.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL11429; CAL11429; YE1340.
GeneIDi4713013.
KEGGiyen:YE1340.
PATRICi18562172. VBIYerEnt11519_1459.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL11429.1.
RefSeqiWP_005171739.1. NC_008800.1.
YP_001005657.1. NC_008800.1.

3D structure databases

ProteinModelPortaliA1JLF1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE1340.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL11429; CAL11429; YE1340.
GeneIDi4713013.
KEGGiyen:YE1340.
PATRICi18562172. VBIYerEnt11519_1459.

Phylogenomic databases

eggNOGiENOG4105DK2. Bacteria.
COG1896. LUCA.
HOGENOMiHOG000276964.
KOiK08722.
OMAiMPTPIKY.
OrthoDBiPOG091H00DC.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
HAMAPiMF_01100. 5DNU. 1 hit.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR022971. YfbR.
[Graphical view]
PfamiPF13023. HD_3. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry namei5DNU_YERE8
AccessioniPrimary (citable) accession number: A1JLF1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.