A1JJT4 (A1JJT4_YERE8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RuleBase RU003490
EC=2.7.7.60 RuleBase RU003490

Gene names

Name:	ispD EMBL CAL10871.1
Ordered Locus Names:	YE0769

Organism

Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [Complete proteome] [HAMAP]

Taxonomic identifier

393305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) By similarity. RuleBase RU003490 SAAS SAAS018294
Catalytic activity	CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. RuleBase RU003490 SAAS SAAS018294
Pathway	Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6. SAAS SAAS018294 RuleBase RU004138
Sequence similarities	Belongs to the IspD family. RuleBase RU004393

Ontologies

Keywords
Biological process	Isoprene biosynthesis SAAS SAAS018294 RuleBase RU004393
Molecular function	Nucleotidyltransferase SAAS SAAS018294 RuleBase RU004393 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	isoprenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1JJT4 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2C7F98750F27646E	FASTA	214	23,443
	10 20 30 40 50 60 MQADCPKQYL IAGGKTIIEH AICSLLGHPR IQRIIVVIHP QDTQFSQLSI ADDPRISMVH 70 80 90 100 110 120 GGDARADSVM AGLQQAGQAE WVLVHDAARP CLHQGDLEKL LAITQHSKVG GILAAPVRDT 130 140 150 160 170 180 MKRSEAGVQA IAHTVDRQAL WHALTPQLFP LELLKMCLSR ALKDGAVVTD EASALEHCGY 190 200 210 HPILVSGRSD NIKVTRPEDL ALAEFYLTQR QYPK

References

[1]

"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081." Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S. , Quail M.A., Dougan G., Parkhill J., Prentice M.B. PLoS Genet. 2:2039-2051(2006) [PubMed: 17173484] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286415 Genomic DNA. Translation: CAL10871.1.
RefSeq	YP_001005110.1. NC_008800.1.
3D structure databases
ProteinModelPortal	A1JJT4.
SMR	A1JJT4. Positions 1-209.
ModBase	Search...
Protein-protein interaction databases
STRING	A1JJT4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4716119.
GenomeReviews	Gene locus YE0769 in contig AM286415_GR.
KEGG	yen:YE0769.
NMPDR	fig|630.2.peg.746.
PATRIC	18560946. VBIYerEnt11519_0862.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1211.
HOGENOM	HBG672839.
OMA	FPQGAIL.
PhylomeDB	A1JJT4.
ProtClustDB	PRK00155.
Enzyme and pathway databases
BioCyc	YENT393305:YE0769-MONOMER.
Family and domain databases
HAMAP	MF_00108. IspD. [Tree]
InterPro	IPR001228. ISPD_synthase. IPR018294. ISPD_synthase_CS. [Graphical view]
KO	K00991.
Pfam	PF01128. IspD. 1 hit. [Graphical view]
TIGRFAMs	TIGR00453. IspD. 1 hit.
PROSITE	PS01295. ISPD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1JJT4_YERE8

Accession

Primary (citable) accession number: A1JJT4

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)