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Protein

Aspartate ammonia-lyase

Gene

aspA

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyaseUniRule annotation (EC:4.3.1.1UniRule annotation)
Short name:
AspartaseUniRule annotation
Gene namesi
Name:aspAImported
Ordered Locus Names:YE0351Imported
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)Imported
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi393305.YE0351.

Structurei

3D structure databases

ProteinModelPortaliA1JIP0.
SMRiA1JIP0. Positions 1-459.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 345333Lyase_1InterPro annotationAdd
BLAST
Domaini411 – 46454FumaraseC_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiEOG6V1M4M.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1JIP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNIRIEED LLGTREVPAE AYYGVHTLRA IENFYISNSK ISDVPEFVRG
60 70 80 90 100
MVMVKKAAAM ANKELHTIPR KIADVIIQAC DEVLDKGKCM DQFPVDVFQG
110 120 130 140 150
GAGTSLNMNT NEVLANIGLE LMGHQKGEYQ YLNPNDHLNK CQSTNDAYPT
160 170 180 190 200
GFRIAVYASI MKLIDAINQL KEGFERKSKE FEKILKMGRT QLQDAVPMTL
210 220 230 240 250
GQEFKAFAVL LKEETKNLQR TAELLLEVNL GATAIGTALN TPEGYSQLAI
260 270 280 290 300
QKLSEISGLP CVPAEDLIEA TSDCGAYVMV HGALKRLAVK MSKICNDLRL
310 320 330 340 350
LSSGPRTGLN EINLPELQAG SSIMPAKVNP VIPEVVNQVC FKVIGNDTCI
360 370 380 390 400
TMAAEAGQLQ LNVMEPVIGQ AMFESIHILT NACYNLLEKC INGITANKEV
410 420 430 440 450
CERYVFNSIG IVTYLNPFIG HHNGDIVGKI CAETGKNVRE VVLERGLLTE
460 470
AELDDIFSVE NLMHPAYKAK RYTDENEQ
Length:478
Mass (Da):52,708
Last modified:February 6, 2007 - v1
Checksum:iF455F6143BC8E81B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL10481.1.
RefSeqiWP_005175569.1. NC_008800.1.
YP_001004727.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL10481; CAL10481; YE0351.
GeneIDi4714362.
KEGGiyen:YE0351.
PATRICi18560100. VBIYerEnt11519_0446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA. Translation: CAL10481.1.
RefSeqiWP_005175569.1. NC_008800.1.
YP_001004727.1. NC_008800.1.

3D structure databases

ProteinModelPortaliA1JIP0.
SMRiA1JIP0. Positions 1-459.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE0351.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL10481; CAL10481; YE0351.
GeneIDi4714362.
KEGGiyen:YE0351.
PATRICi18560100. VBIYerEnt11519_0446.

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiEOG6V1M4M.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 13174 / 8081Imported.

Entry informationi

Entry nameiA1JIP0_YERE8
AccessioniPrimary (citable) accession number: A1JIP0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 16, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.