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A1JIM8

- TDCC_YERE8

UniProt

A1JIM8 - TDCC_YERE8

Protein

Threonine/serine transporter TdcC

Gene

tdcC

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).UniRule annotation

    GO - Molecular functioni

    1. serine transmembrane transporter activity Source: InterPro
    2. symporter activity Source: UniProtKB-HAMAP
    3. threonine efflux transmembrane transporter activity Source: InterPro

    Keywords - Biological processi

    Amino-acid transport, Symport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Threonine/serine transporter TdcCUniRule annotation
    Alternative name(s):
    H(+)/threonine-serine symporterUniRule annotation
    Gene namesi
    Name:tdcCUniRule annotation
    Ordered Locus Names:YE0337
    OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
    Taxonomic identifieri393305 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000642: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 442442Threonine/serine transporter TdcCPRO_0000309176Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi393305.YE0337.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4121HelicalUniRule annotationAdd
    BLAST
    Transmembranei44 – 6421HelicalUniRule annotationAdd
    BLAST
    Transmembranei96 – 11621HelicalUniRule annotationAdd
    BLAST
    Transmembranei139 – 15921HelicalUniRule annotationAdd
    BLAST
    Transmembranei162 – 18221HelicalUniRule annotationAdd
    BLAST
    Transmembranei206 – 22621HelicalUniRule annotationAdd
    BLAST
    Transmembranei258 – 27821HelicalUniRule annotationAdd
    BLAST
    Transmembranei312 – 33221HelicalUniRule annotationAdd
    BLAST
    Transmembranei364 – 38421HelicalUniRule annotationAdd
    BLAST
    Transmembranei388 – 40821HelicalUniRule annotationAdd
    BLAST
    Transmembranei422 – 44221HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0814.
    HOGENOMiHOG000270787.
    KOiK03838.
    OMAiKVMSFLV.
    OrthoDBiEOG6X10TH.

    Family and domain databases

    HAMAPiMF_01583. Thr_Ser_transp_TdcC.
    InterProiIPR013057. AA_transpt_TM.
    IPR004694. Hydroxy_aa_transpt.
    IPR023726. Thr/Ser_transpt_TdcC.
    [Graphical view]
    PfamiPF01490. Aa_trans. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00814. stp. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1JIM8-1 [UniParc]FASTAAdd to Basket

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    MHIDNAITTT IETKTWRKSD TTWTLGLFGT AIGAGVLFFP IRAGFGGLIP    50
    ILIMLVLAYP IAFLCHRALA RLCLSGSNCS GNITETVEEH FGKTGGVVIT 100
    FLYFFAICPL LWIYGVTITN TFMTFWENQL QLAPLNRGVV ALALLLLMAV 150
    VIYFGKDLMV KVMSFLVFPF IACLVLISLS LIPYWNASVI EQVDLSQISL 200
    LGHDGILVTV WLGISIMVFS FNFSPIVSSF VVSKREEYEP EFGREYTEKK 250
    CSQIISRASI LMVAVVMFFA FSCLFTLSPQ NMAEAKAQNI PVLSYLANHF 300
    SSMAGSRSTF SITLEYAASL IALVAIFKSF FGHYLGTLEG LNGLVIKFGY 350
    KGDKTKISSG KLNLISMFFI MGSTWLVAYI NPNILDLIEA MGAPIIASLL 400
    CLLPMYAIHK LPSLARFRGR PENYFVTIVG LLTIFNIVYK LL 442
    Length:442
    Mass (Da):48,950
    Last modified:February 6, 2007 - v1
    Checksum:iDFBFC6AF532A7EF1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL10467.1.
    RefSeqiYP_001004715.1. NC_008800.1.

    Genome annotation databases

    EnsemblBacteriaiCAL10467; CAL10467; YE0337.
    GeneIDi4714347.
    KEGGiyen:YE0337.
    PATRICi18560070. VBIYerEnt11519_0432.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286415 Genomic DNA. Translation: CAL10467.1 .
    RefSeqi YP_001004715.1. NC_008800.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393305.YE0337.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL10467 ; CAL10467 ; YE0337 .
    GeneIDi 4714347.
    KEGGi yen:YE0337.
    PATRICi 18560070. VBIYerEnt11519_0432.

    Phylogenomic databases

    eggNOGi COG0814.
    HOGENOMi HOG000270787.
    KOi K03838.
    OMAi KVMSFLV.
    OrthoDBi EOG6X10TH.

    Family and domain databases

    HAMAPi MF_01583. Thr_Ser_transp_TdcC.
    InterProi IPR013057. AA_transpt_TM.
    IPR004694. Hydroxy_aa_transpt.
    IPR023726. Thr/Ser_transpt_TdcC.
    [Graphical view ]
    Pfami PF01490. Aa_trans. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00814. stp. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 13174 / 8081.

    Entry informationi

    Entry nameiTDCC_YERE8
    AccessioniPrimary (citable) accession number: A1JIM8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3