A1JHX0DUT_YERE8Deoxyuridine 5'-triphosphate nucleotidohydrolasedUTPase3.6.1.23dUTP pyrophosphatasedutYE0061Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)BacteriaPseudomonadotaGammaproteobacteriaEnterobacteralesYersiniaceaeYersiniaThe complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.dUTP + H2O = diphosphate + dUMP + H(+)Mg(2+)Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.Belongs to the dUTPase family.HydrolaseMagnesiumMetal-bindingNucleotide metabolismsubstratesubstratesubstratesubstrateMKKIDIKILDPRVGNEFPLPTYATEGSAGLDLRACLSEAVDLLPGQTTLLPTGLAIHIGDSSLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGQLMVSVWNRGQQPFTIEPGERIAQMVFVPVIQAEFNLVEDFDLSERGTGGFGHSGRQ
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