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A1JHW9

- SLMA_YERE8

UniProt

A1JHW9 - SLMA_YERE8

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Protein

Nucleoid occlusion factor SlmA

Gene
slmA, YE0060
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi33 – 5220H-T-H motif By similarityAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. negative regulation of barrier septum assembly Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoid occlusion factor SlmA
Gene namesi
Name:slmA
Ordered Locus Names:YE0060
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000642: Chromosome

Subcellular locationi

Cytoplasmnucleoid By similarity UniRule annotation

GO - Cellular componenti

  1. bacterial nucleoid Source: UniProtKB-HAMAP
  2. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Nucleoid occlusion factor SlmAUniRule annotationPRO_1000070538Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity. Interacts with FtsZ By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi393305.YE0060.

Structurei

3D structure databases

ProteinModelPortaliA1JHW9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 7062HTH tetR-typeAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili119 – 14426 Reviewed predictionAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000266053.
KOiK05501.
OMAiEKDTSAR.
OrthoDBiEOG6G7R3C.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
HAMAPiMF_01839. NO_factor_SlmA.
InterProiIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR023769. NO_SlmA.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1JHW9-1 [UniParc]FASTAAdd to Basket

« Hide

MAEKENTKRN RREEILQALA QMLESSDGSQ RITTAKLAAN VGVSEAALYR    50
HFPSKTRMFD SLIEFIEDSL MSRINLILQD EKETFNRLRL ILLLVLGFAE 100
RNPGLTRIMT GHALMFEQDR LQGRINQLFE RIEVQLRQVL REKKLRDGQG 150
FIHDEALLAT QLLAFCEGML SRFVRSEFRY RPTQEFDARW PLIVAQLQ 198
Length:198
Mass (Da):23,112
Last modified:February 6, 2007 - v1
Checksum:i8A147A9A9CAE5785
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286415 Genomic DNA. Translation: CAL10202.1.
RefSeqiYP_001004454.1. NC_008800.1.

Genome annotation databases

EnsemblBacteriaiCAL10202; CAL10202; YE0060.
GeneIDi4715151.
KEGGiyen:YE0060.
PATRICi18559455. VBIYerEnt11519_0148.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286415 Genomic DNA. Translation: CAL10202.1 .
RefSeqi YP_001004454.1. NC_008800.1.

3D structure databases

ProteinModelPortali A1JHW9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 393305.YE0060.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL10202 ; CAL10202 ; YE0060 .
GeneIDi 4715151.
KEGGi yen:YE0060.
PATRICi 18559455. VBIYerEnt11519_0148.

Phylogenomic databases

eggNOGi COG1309.
HOGENOMi HOG000266053.
KOi K05501.
OMAi EKDTSAR.
OrthoDBi EOG6G7R3C.

Family and domain databases

Gene3Di 1.10.357.10. 1 hit.
HAMAPi MF_01839. NO_factor_SlmA.
InterProi IPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR023769. NO_SlmA.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view ]
Pfami PF00440. TetR_N. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEi PS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 13174 / 8081.

Entry informationi

Entry nameiSLMA_YERE8
AccessioniPrimary (citable) accession number: A1JHW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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