A1IR14 (A1IR14_NEIMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

NMA0974

Organism

Neisseria meningitidis serogroup A / serotype 4A (strain Z2491) [Complete proteome] [HAMAP]

Taxonomic identifier

122587 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria meningitidis › Neisseria meningitidis serogroup A

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Lyase EMBL CAM08198.1 Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular_function	cysteine synthase activity Inferred from electronic annotation. Source: EC transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1IR14 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: FE9C74BF7C2AFD7A	FASTA	310	32,821
	10 20 30 40 50 60 MKIANSITEL IGNTPLVKLN RLTEGLKAEV AVKLEFFNPG SSVKDRIAEA MIEGAEKAGK 70 80 90 100 110 120 INKNTVIVEA TSGNTGVGLA MVCAARGYKL AITMPESMSK ERKMLLRAFG AELILTPAAE 130 140 150 160 170 180 GMAGAIAKAK SLVDAHPDTY FMPRQFDNEA NPEVHRKTTA EEIWRDTDGK VDVFVAGVGT 190 200 210 220 230 240 GGTITGVGEV LKKYKPEVKV VAVEPEASPV LSGGEKGPHP IQGIGAGFIP TVLNTKIYDS 250 260 270 280 290 300 ITKVSNEAAF ETARAIAEKE GILVGISSGA AVWSALQLAK QPENEGKLIV VLLPSYGERY 310 LSTPLFADLA

References

[1]

"Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491." Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M., Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S. , Moule S., Mungall K.L., Quail M.A., Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G., Barrell B.G. Nature 404:502-506(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z2491.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL157959 Genomic DNA. Translation: CAM08198.1.
PIR	H81161.
RefSeq	YP_002342396.1. NC_003116.1.
3D structure databases
ProteinModelPortal	A1IR14.
SMR	A1IR14. Positions 1-307.
ModBase	Search...
Protein-protein interaction databases
STRING	122587.NMA0974.
Proteomic databases
PRIDE	A1IR14.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAM08198; CAM08198; NMA0974.
GeneID	906951.
KEGG	nma:NMA0974.
PATRIC	20362864. VBINeiMen132687_1141.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000217394.
KO	K01738.
OMA	DMANQLK.
ProtClustDB	CLSK877729.
Enzyme and pathway databases
BioCyc	NMEN122587:GI3Q-888-MONOMER.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. Trp_syn_b_sub_like_PLP_eny_SF. [Graphical view]
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. cysK. 1 hit. TIGR01136. cysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1IR14_NEIMA

Accession

Primary (citable) accession number: A1IR14

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)