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Protein
Submitted name:

Putative prohormone convertase 2

Gene

CiPC2

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS08.073.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative prohormone convertase 2Imported (EC:3.4.21.94Imported)
Gene namesi
Name:CiPC2Imported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000011797.

Structurei

3D structure databases

ProteinModelPortaliA1IHD0.
SMRiA1IHD0. Positions 145-622.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG4935.
HOVERGENiHBG008705.
KOiK01360.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1IHD0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADNCYAGQT RSFSRALSYI LLLTLMSWDT DLAGIRTGSL LVSAAKKRVY
60 70 80 90 100
TNDFLVTIKS AEPSSNHDHA DWLAARHGFE NRGMVVGDEG LYHFRHRTLD
110 120 130 140 150
SASESPSLRY IWNLRLSPKV QKVRQLEGYG RLKRGHNKVK VGAYQGLDPL
160 170 180 190 200
YPYQWYINNT GQAGGKPGLD LNVQAAWNMG YTGKGVTVAI MDDGLDYLHP
210 220 230 240 250
DLRDNYSPEA SYDFSSNDPY PYPRYTFNWF NSHGTRCAGE VSSVADNGIC
260 270 280 290 300
GVGVAYDSKI AGIRMLDQPF MTDVIEAASM SFKPNLIDIY SASWGPTDDG
310 320 330 340 350
KTVDGPRQLT LRAIVNGVNK GRNGLGSIYV WASGDGGADD DCNCDGYAAS
360 370 380 390 400
MWTISVNSAI NDGETALYDE SCSSTLASTF SNGRGQRAGS GVATTDLYGQ
410 420 430 440 450
CTLRHSGTSA AAPEAAGVFA LALDANKNLT WRDVQHLTVL TSTPNLLHDD
460 470 480 490 500
LHRWQSNGVG LMFNHLFGFG VLNAQKMVKM AKTWTTVPPR FRCEAGVVEQ
510 520 530 540 550
MFDIPSDGVL ELTIDTDACD GGNNHVRYLE HVQAFLTIAS SRRGDLTINM
560 570 580 590 600
TSPFGTDSIL LNRRPNDDDS SQGFRKWPFM TTHTWGEDPR GTWKLRVALN
610 620 630 640 650
GEFPQTGRLL RWGLLLHGTQ QAPYIDEILD GHNSKLAVSK KLEFAEGILH
660
DLEDSGSQHP
Length:660
Mass (Da):72,590
Last modified:February 6, 2007 - v1
Checksum:iD03A15473DB6E005
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB250763 mRNA. Translation: BAF42696.1.
RefSeqiNP_001128498.1. NM_001135026.1.
UniGeneiCin.32722.

Genome annotation databases

GeneIDi100181292.
KEGGicin:100181292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB250763 mRNA. Translation: BAF42696.1.
RefSeqiNP_001128498.1. NM_001135026.1.
UniGeneiCin.32722.

3D structure databases

ProteinModelPortaliA1IHD0.
SMRiA1IHD0. Positions 145-622.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7719.ENSCINP00000011797.

Protein family/group databases

MEROPSiS08.073.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100181292.
KEGGicin:100181292.

Organism-specific databases

CTDi100181292.

Phylogenomic databases

eggNOGiCOG4935.
HOVERGENiHBG008705.
KOiK01360.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Further EST analysis of endocrine genes that are preferentially expressed in the neural complex of Ciona intestinalis: receptor and enzyme genes associated with endocrine system in the neural complex."
    Sekiguchi T., Kawashima T., Satou Y., Satoh N.
    Gen. Comp. Endocrinol. 150:233-245(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA1IHD0_CIOIN
AccessioniPrimary (citable) accession number: A1IHD0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.