A1F9M2 (A1F9M2_VIBCH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate carbamoyltransferase HAMAP MF_00001
EC=2.1.3.2 HAMAP MF_00001

Alternative name(s):
Aspartate transcarbamylase HAMAP MF_00001

Gene names

Name:	pyrB HAMAP MF_00001 EMBL EAX57055.1
ORF Names:	VC274080_2522 EMBL EAX57055.1

Organism

Vibrio cholerae 2740-80 EMBL EAX57055.1

Taxonomic identifier

412614 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001
Sequence similarities	Belongs to the ATCase/OTCase family. HAMAP MF_00001 RuleBase RU003634

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis HAMAP MF_00001
Molecular function	Transferase HAMAP MF_00001 RuleBase RU003634 EMBL EAX57055.1
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1F9M2 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: E3556D0CD954BEAE	FASTA	330	36,759
	10 20 30 40 50 60 MLKPPLWGAF LWLLENIGKT IMANSLYQKH IISIAELSRA ELELIVKTAG QLKAQPNPEL 70 80 90 100 110 120 IKHKVVASCF FEPSTRTRLS FETAIQRIGG SVIGFDNGGN TSLAKKGETL ADSVRVISSY 130 140 150 160 170 180 VDAFVMRHPQ EGAARLASEF SNGVPVINAG DGSNQHPSQT LLDLYSIFET QGRLDNLDVA 190 200 210 220 230 240 FVGDLKYGRT VHSLAQALAK FDNNRFYFVA PEALAMPDYI CEELDEAGVK YQVFSDMESV 250 260 270 280 290 300 IPELDILYMT RVQKERFDES EYAHIKSAYI LTAAHLSDAR SNLKVLHPLP RVDEITTDVD 310 320 330 KTPHAYYFEQ VENGVYAREA LLALVLNESL

References

[1]	Heidelberg J., Sebastian Y. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 2740-80 EMBL EAX57055.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAUT01000088 Genomic DNA. Translation: EAX57055.1.
3D structure databases
ProteinModelPortal	A1F9M2.
SMR	A1F9M2. Positions 23-330.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	28014717. VBIVibCho84837_3187.
Family and domain databases
HAMAP	MF_00001. Asp_carb_tr. [Tree]
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002082. Asp_carbamoyltransf_euk. [Graphical view]
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00101. ATCASE.
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMs	TIGR00670. Asp_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1F9M2_VIBCH

Accession

Primary (citable) accession number: A1F9M2

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)