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Protein
Submitted name:

Matrix metallopeptidase 28

Gene

Mmp28

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Zn2+SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei241UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseSAAS annotation, Protease
LigandMetal-bindingSAAS annotation, ZincSAAS annotation

Protein family/group databases

MEROPSiM10.030

Names & Taxonomyi

Protein namesi
Submitted name:
Matrix metallopeptidase 28Imported
Submitted name:
Matrix metalloproteinase 28Imported
Gene namesi
Name:Mmp28Imported
Synonyms:LOC100912318Imported, LOC103694864Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi9149208 LOC103694864
1311573 Mmp28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501508590623 – 525Sequence analysisAdd BLAST503

Expressioni

Gene expression databases

BgeeiENSRNOG00000047940

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060554

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini126 – 285ZnMcInterPro annotationAdd BLAST160
Repeati325 – 369HemopexinPROSITE-ProRule annotationAdd BLAST45
Repeati370 – 424HemopexinPROSITE-ProRule annotationAdd BLAST55
Repeati461 – 508HemopexinPROSITE-ProRule annotationAdd BLAST48

Sequence similaritiesi

Belongs to the peptidase M10A family.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1565 Eukaryota
ENOG410XQ5D LUCA
GeneTreeiENSGT00910000144034
HOGENOMiHOG000217927
HOVERGENiHBG052484
KOiK08006
OMAiYCHSSFD
OrthoDBiEOG091G03DP
TreeFamiTF315428

Family and domain databases

CDDicd00094 HX, 1 hit
cd04278 ZnMc_MMP, 1 hit
Gene3Di2.110.10.10, 1 hit
3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR000585 Hemopexin-like_dom
IPR036375 Hemopexin-like_dom_sf
IPR018487 Hemopexin-like_repeat
IPR033739 M10A_MMP
IPR024079 MetalloPept_cat_dom_sf
IPR028735 MMP28
IPR001818 Pept_M10_metallopeptidase
IPR021190 Pept_M10A
IPR006026 Peptidase_Metallo
IPR002477 Peptidoglycan-bd-like
IPR036365 PGBD-like_sf
PANTHERiPTHR10201:SF16 PTHR10201:SF16, 1 hit
PfamiView protein in Pfam
PF00045 Hemopexin, 3 hits
PF00413 Peptidase_M10, 1 hit
PF01471 PG_binding_1, 1 hit
PIRSFiPIRSF001191 Peptidase_M10A_matrix, 1 hit
PRINTSiPR00138 MATRIXIN
SMARTiView protein in SMART
SM00120 HX, 4 hits
SM00235 ZnMc, 1 hit
SUPFAMiSSF47090 SSF47090, 1 hit
SSF50923 SSF50923, 1 hit
PROSITEiView protein in PROSITE
PS51642 HEMOPEXIN_2, 3 hits

Sequencei

Sequence statusi: Complete.

A1EC81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTGLSLLLR VLPLLLWGCQ DAQPTPRGHP ELHQEAEAFL EKYGYLSEQG
60 70 80 90 100
SKVPASTQFS DAIREFQWVS QLPISGVLDR ATLRQMTRPR CGVADTDSHE
110 120 130 140 150
TWTERIRALL AGHRAKMRRK KRFAKPGHKW YKQHLSYRLV NWPKSLPEPA
160 170 180 190 200
VRGAVRAAFQ LWSNVSALEF WEAPATGPAD IRLTFFQGDH NDGLANAFDG
210 220 230 240 250
PGGALAHAFL PRRGEAHFDQ DERWSLSRRR GRNLFVVLAH EIGHTLGLTH
260 270 280 290 300
SPAPRALMAP YYKKLGRDAL LSWDDVLAVQ NLYGKPLGRS VATQLPGKIF
310 320 330 340 350
TDFEAWDPHN SQSRRPETRG PKYCHSSFDA ITVDGQWRLY VFKGSHFWEV
360 370 380 390 400
TADGNVSEPH PLQKRWPGLP SSIEAAAVSL EDGDFFFFKG NRCWRFQGTK
410 420 430 440 450
SVFAQLCRAG GLPRHPDAAL FFPPLRRLVL FKGSRYYVLA RGGMQVEPYY
460 470 480 490 500
PRSLRDWAGV PEEVSGALPR PDGSIIFFRD DHYWHLDQAK LRVTSSGRWA
510 520
TELSWMGCWN ANSGGALFQR LPVTE
Length:525
Mass (Da):59,436
Last modified:January 23, 2007 - v1
Checksum:i5975E21F30768EB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC119615 Genomic DNA No translation available.
EF121988 mRNA Translation: ABL63427.1
RefSeqiNP_001073357.1, NM_001079888.1
XP_008772033.1, XM_008773811.2
UniGeneiRn.60472

Genome annotation databases

EnsembliENSRNOT00000013836; ENSRNOP00000013836; ENSRNOG00000047940
ENSRNOT00000083214; ENSRNOP00000075186; ENSRNOG00000061904
GeneIDi103694864
303384
KEGGirno:103694864
rno:303384

Similar proteinsi

Entry informationi

Entry nameiA1EC81_RAT
AccessioniPrimary (citable) accession number: A1EC81
Secondary accession number(s): D3ZNN5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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