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A1E960 (ODAM_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Odontogenic ameloblast-associated protein
Alternative name(s):
Apin
Gene names
Name:Odam
Synonyms:Apin
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Highly expressed in tooth-associated epithelia. Predominantly expressed in mandible. Ref.4

Post-translational modification

O-glycosylated By similarity.

Sequence similarities

Belongs to the ODAM family.

Sequence caution

The sequence AAI32395.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAI32397.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAB26200.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1515 Potential
Chain16 – 273258Odontogenic ameloblast-associated protein
PRO_5000183880

Regions

Compositional bias62 – 196135Gln-rich

Amino acid modifications

Glycosylation1141O-linked (GalNAc...) Potential
Glycosylation1181O-linked (GalNAc...) Potential
Glycosylation1591O-linked (GalNAc...) Potential
Glycosylation2401O-linked (GalNAc...) Potential
Glycosylation2411O-linked (GalNAc...) Potential
Glycosylation2471O-linked (GalNAc...) Potential
Glycosylation2521O-linked (GalNAc...) Potential
Glycosylation2581O-linked (GalNAc...) Potential
Glycosylation2671O-linked (GalNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1E960 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: CA8B395AE68985B6

FASTA27329,820
        10         20         30         40         50         60 
MKIIILLGLI GASSSAPLIS QRLLSASNSH ELLLNLNNGQ LLPLQFQGAF NSWIPPFPGF 

        70         80         90        100        110        120 
LQQQQAQVSG RPQFTLSTLE SFAGLFPNQI PLSRQVGLAQ GGQAGQPDLS QQQTPPQTQQ 

       130        140        150        160        170        180 
SASPMSYVVP VKVPQDQTQM FQYYPVYMLL PWEQPQTVTS SPQHTGQQLF EEQIPFYNQF 

       190        200        210        220        230        240 
GFAPPQAEPG VPGGQQHLAF DSFVGTAPET PGMPVEGSLL YPQKEPISFK HDNAGVFMPT 

       250        260        270 
TSPKPSTDNF FTSGIDPTIA PEQKVKTDSL REP 

« Hide

References

« Hide 'large scale' references
[1]Moffatt P., Smith C.E., Nanci A.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: CD-1.
Tissue: Mandible.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 105-273.
Strain: C57BL/6J.
Tissue: Tongue.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 114-273.
Tissue: Brain.
[4]"Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia."
Moffatt P., Smith C.E., St Arnaud R., Nanci A.
J. Cell. Biochem. 103:941-956(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EF113909 mRNA. Translation: ABL11578.1.
AK009298 mRNA. Translation: BAB26200.1. Different initiation.
BC132394 mRNA. Translation: AAI32395.1. Different initiation.
BC132396 mRNA. Translation: AAI32397.1. Different initiation.
CCDSCCDS19394.2.
RefSeqNP_081404.2. NM_027128.2.
XP_006535273.1. XM_006535210.1.
UniGeneMm.389652.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000108899.

Proteomic databases

PRIDEA1E960.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000113274; ENSMUSP00000108899; ENSMUSG00000009580.
ENSMUST00000129757; ENSMUSP00000117898; ENSMUSG00000009580.
GeneID69592.
KEGGmmu:69592.
UCSCuc008xzd.1. mouse.

Organism-specific databases

CTD54959.
MGIMGI:1916842. Odam.

Phylogenomic databases

eggNOGNOG74202.
GeneTreeENSGT00390000011100.
HOGENOMHOG000115257.
HOVERGENHBG096669.
InParanoidA1E960.
OMANSWIPPF.
OrthoDBEOG7673CG.
PhylomeDBA1E960.
TreeFamTF338424.

Gene expression databases

BgeeA1E960.
CleanExMM_ODAM.
GenevestigatorA1E960.

Family and domain databases

InterProIPR026802. Odam.
[Graphical view]
PANTHERPTHR16237. PTHR16237. 1 hit.
PfamPF15424. ODAM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio329866.
PROA1E960.
SOURCESearch...

Entry information

Entry nameODAM_MOUSE
AccessionPrimary (citable) accession number: A1E960
Secondary accession number(s): Q9D7E6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot