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Protein

Probable beta-glucosidase H

Gene

bglH

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi: cellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei225By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase H (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase H
Cellobiase H
Gentiobiase H
Gene namesi
Name:bglH
ORF Names:NFIA_060370
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_060370.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003948821 – 829Probable beta-glucosidase HAdd BLAST829

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi13N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi304N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi473N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi602N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi627N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi664N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00004863.

Structurei

3D structure databases

ProteinModelPortaliA1DPG0.
SMRiA1DPG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini389 – 548PA14PROSITE-ProRule annotationAdd BLAST160

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Phylogenomic databases

HOGENOMiHOG000031215.
KOiK05349.
OMAiCESTGVI.
OrthoDBiEOG092C0SKR.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
3.20.20.300. 2 hits.
3.40.50.1700. 2 hits.
InterProiView protein in InterPro
IPR026891. Fn3-like.
IPR008979. Galactose-bd-like_sf.
IPR002772. Glyco_hydro_3_C.
IPR036881. Glyco_hydro_3_C_sf.
IPR001764. Glyco_hydro_3_N.
IPR036962. Glyco_hydro_3_N_sf.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR037524. PA14/GLEYA.
IPR011658. PA14_dom.
PfamiView protein in Pfam
PF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
PF07691. PA14. 1 hit.
PRINTSiPR00133. GLHYDRLASE3.
SMARTiView protein in SMART
SM01217. Fn3_like. 1 hit.
SM00758. PA14. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiView protein in PROSITE
PS51820. PA14. 1 hit.

Sequencei

Sequence statusi: Complete.

A1DPG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKFDVDYV LANITEDDKI ALLSGSDFWH THAIPKFNVP PIRTTDGPNG
60 70 80 90 100
IRGTKFFAGV PAACLPCGTA LGATWDRDLL HQAGVLLGKE CLAKGAHCWL
110 120 130 140 150
GPTINMQRSP LGGRGFESFA EDPHLSGIMA KSIILGCEST GVISTVKHYV
160 170 180 190 200
GNDQEHERRA VDVLVTPRAL REIYLRPFQI VARDAHPGAL MTSYNKINGK
210 220 230 240 250
HVVENPAMLD IVRKDWNWDP LIMSDWLGTY TTIDSMNAGL DLEMPGPTRY
260 270 280 290 300
RGKYIESAMQ ARLIKQSTIN KRARKVLEFV QRASRAPVSA DETGRDFPED
310 320 330 340 350
RALNRTLCAN SIVLLKNDGN LLPIPKTVKK IALIGSHVKT PAISGGGSAS
360 370 380 390 400
LEPYYAVSLY DAVVEALPDA KILYEAGAYA HKMLPVIDRM LSNAVIHFYN
410 420 430 440 450
EPPEKERTLL ATEPVVNTAF QLMDYNAPGL NRGLFWATLI GEFTPDVSGL
460 470 480 490 500
WDFGLTVFGT ATLFVDDEMV IDNTTRQTRG TAFFGKGTVQ EVGQKQLTAG
510 520 530 540 550
QTYKIRIEFG SANTSPMKAI GVVHFGGGAA HLGACLHMDP EQMVANAVKV
560 570 580 590 600
AAEADYTIVC TGLNRDWESE GFDRPDMDLP PGIDALISSV LDLAADRTVI
610 620 630 640 650
VNQSGTPVTL PWADRARGVV QAWYGGNETG HGIADVLFGD VNPCGKLPLS
660 670 680 690 700
WPVDVKHNPA YLNNMSVGGR MLYGEDVYMG YRFYEKVGRE VLFPFGHGLS
710 720 730 740 750
YTTFSVSPEA TVSPSVFSSD SPPTARVLVK NTGPVAGAQI LQLYIAAPNS
760 770 780 790 800
ATPRPVKELH GFTKVFLQPG EERTVAIHID KYATSFWDEI EDMWKSEEGV
810 820
YQVLIGTSSQ EIVSRGEFRV EQTRYWRGV
Length:829
Mass (Da):90,819
Last modified:January 23, 2007 - v1
Checksum:i76A219B2EEEF9D68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027698 Genomic DNA. Translation: EAW16681.1.
RefSeqiXP_001258578.1. XM_001258577.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00004991; CADNFIAP00004863; CADNFIAG00004991.
GeneIDi4585094.
KEGGinfi:NFIA_060370.

Similar proteinsi

Entry informationi

Entry nameiBGLH_NEOFI
AccessioniPrimary (citable) accession number: A1DPG0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome