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Protein

Autophagy-related protein 2

Gene

atg2

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes completion and in peroxisome degradation.By similarity

GO - Biological processi

Keywordsi

Biological processAutophagy, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Autophagy-related protein 2
Gene namesi
Name:atg2
ORF Names:NFIA_059120
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_059120.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003178091 – 2137Autophagy-related protein 2Add BLAST2137

Proteomic databases

PRIDEiA1DP40.

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00004917.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG2 family.Curated

Phylogenomic databases

HOGENOMiHOG000034150.
KOiK17906.
OMAiFDHVPTS.
OrthoDBiEOG092C02NM.

Family and domain databases

InterProiView protein in InterPro
IPR026849. ATG2.
IPR026885. ATG2_CAD_motif.
IPR026886. ATG2_fungi/plants.
IPR015412. Autophagy-rel_C.
PANTHERiPTHR13190. PTHR13190. 1 hit.
PTHR13190:SF1. PTHR13190:SF1. 1 hit.
PfamiView protein in Pfam
PF13329. ATG2_CAD. 1 hit.
PF09333. ATG_C. 1 hit.

Sequencei

Sequence statusi: Complete.

A1DP40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYFLPSFFQ KRLLRYALSR LELVDTEALD LDSLGIRWGQ RSTVELRDIG
60 70 80 90 100
LRLEKLATLL QLPASSELLS AKVQFLKITV PADIYSSGII CEASGINVHL
110 120 130 140 150
QLPSEESFGA AKDENPNSRR PSQAGTHDSS SDHILPTPAD LAESFLDAEP
160 170 180 190 200
KEEKEELQAA ITSRSQVLHR TSASISDDEE ELGLGNEGVS LPSFVAAFLK
210 220 230 240 250
GVAERLQVKV DNVSIRVDME TKQEGVVKRE PENKPDNVTG LLTVREVSVG
260 270 280 290 300
AVSSATSSSE EEKLSRNRNR PIVISDINMA LISEPIVFSN YSRFAPPTSP
310 320 330 340 350
TTPVQPKSSE PSSRIPSPLP GQASDADSVL AMTRSTILEP SQEHSIQDIE
360 370 380 390 400
EPGVGRMEGS AYTYDGRFSD ADTDDENRSD GYLEGSQQFL DDDKLLDNPA
410 420 430 440 450
YLDSVIDSQL HDDDLEPPED LVPQDDQFPP SSETLRSQTP EVHMHRETSP
460 470 480 490 500
SNIDTEHTAP FSHYGDGSFM DRSPHGSQPY LETDHVATPD VSHSASSPSG
510 520 530 540 550
SLPSRENSDR QTAPPSESGS VGSSDVANGG ELSESKLFSN EEAQSMYMSA
560 570 580 590 600
ISHGSSRSFV PNIPGAWDLP ESTVVRDVHA GTQLTDAADA KQDVQDETLI
610 620 630 640 650
STPKLTAQAA SALTEKRSFG EQSECPSEAR EPDLTPLSPT LSKLSDVAKR
660 670 680 690 700
FLRIDRISIS IPVGEDRRHT DETVRSADVN SASDSLKDSA MRSGHSSTES
710 720 730 740 750
ELLSSTMYAS ARLRSDSISS EPSFEGTLPR SPPRQANKAD HGPISKSQPG
760 770 780 790 800
DIAVEISAVD VRFDNAIGWL VVKTGQRVLH AFRDGGNVSS GKPAPESVQT
810 820 830 840 850
RHSLALTLHN FCIKYVDHIP GQTYALNDYD PHSSSPFGLP HEDIILRATA
860 870 880 890 900
SGLTARYLAD KNVTKFGLDV SKFVFGFASD DLISFSESLK MRESTRDVLS
910 920 930 940 950
PVNGDISLSL TKSSDSASLT ITTLPLRLYL NVQRLEEVFG RVGGLSTILE
960 970 980 990 1000
LGNSISSVSS GKNMKRDSQR RARGVHFESS PPPENNLQAN PQLSWKVNAR
1010 1020 1030 1040 1050
VGGIVFDVAG ETHYLRLKTT AVKVVSRFEG IGVQIDKAKL SGPLPLDDSR
1060 1070 1080 1090 1100
DAPAKINLSN IRVEFLYSPK EPDLDRLLAI ITPSKDKYDE DDDIMLDTLF
1110 1120 1130 1140 1150
RQRRQGSVLR TTVAGAKIVV SRTSDLESLS QLEEELGKLS TVAKYLPEDD
1160 1170 1180 1190 1200
RPGILTLTLI RELESQVYLG GPVGNITTHL RNAEAAYISM PSLIAAQLGT
1210 1220 1230 1240 1250
IKVVRNGSEE LVGEALPASG SQGQNQSQLP ILMARYIADE MDPTIKIKSH
1260 1270 1280 1290 1300
NLRVEYTIPS IIAFLGLSED QTTGDVAANM ANSLANIAES QHLHRNASEI
1310 1320 1330 1340 1350
SIGSKGRQAS AKPSRLAFAL RDCVLGLNPR GTTAKGLVVL TNAKFSAAIS
1360 1370 1380 1390 1400
DSGCSEAMLD IKKASIMLID DVKNMGLAEN LHRGRSTIPQ SDQIQSFIDM
1410 1420 1430 1440 1450
GFVPVSSISS AMATVKLMQL DDDGTKSLDV ELKDDLLILE TCADSTQTLI
1460 1470 1480 1490 1500
SIINGLQPPT PPSVAVKYRT EVLPIEDMLA SFSGDAFAMD PPPEQAEIPE
1510 1520 1530 1540 1550
APTIVEPEDG GPGIEDELEY VSDFYPVKSG PDNLPPNESA VPSESNDLLD
1560 1570 1580 1590 1600
SFHSQYYVSS SVSDLEFKED HFANHSAVGG TAHRWDSTQN TYGLTDDSKI
1610 1620 1630 1640 1650
RKSPLRIRVR DAHIIWNLFD GYDWQRTRDT ISKAVKDVEK RATERRARAG
1660 1670 1680 1690 1700
SRASPGFEEE EESVIGDCLF NSIYIGIPAN KDPRELRNDI NHNIDDLASE
1710 1720 1730 1740 1750
TGSYATTTTV TGATARQGQS PSYRGRRLKL SRSKYHKMTF ELKGICADFV
1760 1770 1780 1790 1800
VFPPGSEETQ SSLDVRVNDL EIFDHVPTST WKKFATYMHE AGERESGASM
1810 1820 1830 1840 1850
VHLEMLTVRP VPELAASELV LKATLLPLRL HVDQDALDFI CRFFEFRDDS
1860 1870 1880 1890 1900
ALTPSSPADI PFLQRVEVNA VPVKLDFKPK RVDYAGLRSG RTTEFMNFFV
1910 1920 1930 1940 1950
LDGADMVMRH VIIYGVSGFD KLGQTLNDIW MPDIKRNQLP GVLAGLAPIR
1960 1970 1980 1990 2000
SLVNVGGGVK DLVVVPMREY RKDGRLVRSI QKGALAFAKT TSNELVKLGA
2010 2020 2030 2040 2050
KLAIGTQTVL QGAEEMLTTP TAPTLGSEED MIDEEEANKI SPYADQPVGV
2060 2070 2080 2090 2100
VQGLRGAFRG LERDLLLARD AIVAVPGEIV ESGSAKAAAR AVFKRAPTVI
2110 2120 2130
LRPAIGVSKA VGQTLLGAGN TLDPSNRRKI EDKYKRH
Length:2,137
Mass (Da):232,859
Last modified:January 23, 2007 - v1
Checksum:i199DF8C61A7637EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027698 Genomic DNA. Translation: EAW16561.1.
RefSeqiXP_001258458.1. XM_001258457.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00005045; CADNFIAP00004917; CADNFIAG00005045.
GeneIDi4584974.
KEGGinfi:NFIA_059120.

Similar proteinsi

Entry informationi

Entry nameiATG2_NEOFI
AccessioniPrimary (citable) accession number: A1DP40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families