Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1DMX4

- EXGD_NEOFI

UniProt

A1DMX4 - EXGD_NEOFI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glucan 1,3-beta-glucosidase D

Gene

exgD

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity).By similarity

Catalytic activityi

Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei600 – 6001Proton donorBy similarity
Active sitei705 – 7051NucleophileBy similarity

GO - Molecular functioni

  1. glucan exo-1,3-beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. polysaccharide catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucan 1,3-beta-glucosidase D (EC:3.2.1.58)
Alternative name(s):
Exo-1,3-beta-glucanase D
Gene namesi
Name:exgD
ORF Names:NFIA_054930
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
ProteomesiUP000006702: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 834834Probable glucan 1,3-beta-glucosidase DPRO_0000395169Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi333 – 3331N-linked (GlcNAc...)Sequence Analysis
Glycosylationi379 – 3791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi384 – 3841N-linked (GlcNAc...)Sequence Analysis
Glycosylationi396 – 3961N-linked (GlcNAc...)Sequence Analysis
Glycosylationi549 – 5491N-linked (GlcNAc...)Sequence Analysis
Glycosylationi561 – 5611N-linked (GlcNAc...)Sequence Analysis
Glycosylationi570 – 5701N-linked (GlcNAc...)Sequence Analysis
Glycosylationi639 – 6391N-linked (GlcNAc...)Sequence Analysis
Glycosylationi672 – 6721N-linked (GlcNAc...)Sequence Analysis
Glycosylationi692 – 6921N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00005040.

Structurei

3D structure databases

ProteinModelPortaliA1DMX4.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 306306CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini328 – 834507ExtracellularSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei307 – 32721Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi6 – 174169Arg-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2730.
HOGENOMiHOG000114462.
KOiK01210.
OMAiNIITHYG.
OrthoDBiEOG7ZPNTV.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

A1DMX4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSHSRSRDR YGGRDSDREA RYDYDYARRR YATDDNDDDY DDDELEHGLN
60 70 80 90 100
ERRYRRDGYL PPRESRTRGY YERDAEGAAD EELLGDERNP GPRASRSYGH
110 120 130 140 150
DYDARRGERS RAREAPRRSE RHRDRDREGQ SRRRAYEDDG RHRTRDGRRE
160 170 180 190 200
RGRESDAEAR RSRRREAGRE TAARKHQSSD STNSASHLLS ADALARLGAQ
210 220 230 240 250
YEKEERRKRE NAKDAAKAER KRQKKRAVVG EESRALRDPP GESHRDRTKA
260 270 280 290 300
RVASGAYLEE GRSPEMQVRH RGGGGPAMEA RWRKEGSWGG TMDDAGGGRP
310 320 330 340 350
FWKRKKWIGL GALILILVIV IPVAVVVSKK HDNKSDPADP QGTSPGKSNL
360 370 380 390 400
DGLSHDSIPA YAQGTYLDPW TWYDTTDFNV TFTNETVGGL SIMGLNSTWD
410 420 430 440 450
DSARPNDNVP PLNEPFPYGS QPIRGVNLGG WLSIEPFIVP SLFDSYSSVA
460 470 480 490 500
GIIDEWTLSK RLGSSAARTL EKHYATFITE QDFADIRDAG LDHVRIQYSY
510 520 530 540 550
WAVATYDDDP YVAKISWRYL LRAIEYCRKY GLRVKLDPHG IPGSQNGWNH
560 570 580 590 600
SGREGVIGWL NGTDGELNRN RSLAVHDSVS KFFAQDRYKN IVTIYGLVNE
610 620 630 640 650
PLMLSLSVED VLDWTTEATK LVQKNGITAY VALHDGFLNL SKWKSMLKNR
660 670 680 690 700
PDKMLLDTHQ YTIFNTGQIG LNHTAKVNLI CNDWYNMIKE INSTSTGWGP
710 720 730 740 750
TICGEWSQAD TDCAKYLNNV GRGTRWEGTF SLTDSTQYCP TADTGPPCSC
760 770 780 790 800
ANANADVSEY SADYKKFLQT YAEAQMSAFE TGQGWFYWTW RTESAAQWSY
810 820 830
RTAWKNGFMP AKAYAPSFKC GDAVPDFGNL PEYY
Length:834
Mass (Da):94,751
Last modified:January 23, 2007 - v1
Checksum:i3C79949E1E4CB32F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027698 Genomic DNA. Translation: EAW16145.1.
RefSeqiXP_001258042.1. XM_001258041.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00005168; CADNFIAP00005040; CADNFIAG00005168.
GeneIDi4584557.
KEGGinfi:NFIA_054930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027698 Genomic DNA. Translation: EAW16145.1 .
RefSeqi XP_001258042.1. XM_001258041.1.

3D structure databases

ProteinModelPortali A1DMX4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 36630.CADNFIAP00005040.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADNFIAT00005168 ; CADNFIAP00005040 ; CADNFIAG00005168 .
GeneIDi 4584557.
KEGGi nfi:NFIA_054930.

Phylogenomic databases

eggNOGi COG2730.
HOGENOMi HOG000114462.
KOi K01210.
OMAi NIITHYG.
OrthoDBi EOG7ZPNTV.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00150. Cellulase. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Entry informationi

Entry nameiEXGD_NEOFI
AccessioniPrimary (citable) accession number: A1DMX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3