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A1DM29 (A1DM29_NEOFI) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length1241 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation By similarity. PIRNR PIRNR037104

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. PIRNR PIRNR037104 SAAS SAAS001214

Subunit structure

Component of the COMPASS (Set1C) complex By similarity. PIRNR PIRNR037104

Subcellular location

Nucleus By similarity PIRNR PIRNR037104.

Sequence similarities

Contains 1 SET domain. RuleBase RU004538

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Sequences

Sequence LengthMass (Da)Tools
A1DM29 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 5410637BC4667BFE

FASTA1,241139,380
        10         20         30         40         50         60 
MSRTSAGFAD FFPTAPSVLQ QKRVRAPRDR SRSKDRPEDQ LQVQDGNGQL ACSSGASAAN 

        70         80         90        100        110        120 
VSTNGSPPSV SVSETGTGVE KPGCKLVEET NTDITGTDTS ILSASLAQCR ATQVNEARFD 

       130        140        150        160        170        180 
NLTPVTNAES SPPRKLSPHQ SKSVSVAEYE SNKFATDELK LAATPLHTPP TPRSQTSRSG 

       190        200        210        220        230        240 
VIKGCKLVYD PDLEKRSSKE KRRKPQYVDF VVNEQDGCSP DPRLSILNYT RGAGCKQKTK 

       250        260        270        280        290        300 
YRPAPYRLKQ WPYDTATTIG PGPPVQIVVT GFDPLTPVAP INALFSSFGE ISEINNRTDP 

       310        320        330        340        350        360 
ITGRFLGVCS VKYKDSTSFR GAGPIPAATA ARRAYVECKK EQRIGTRRIR VELDRDGAVS 

       370        380        390        400        410        420 
DRIVARAIES QRMGHKKNTV GEEAKIEPQA KKNEPPPTAP KGPSRSSTRP AAAVPEGPRA 

       430        440        450        460        470        480 
SFLKPAMPSL IEETPILGQI KRDPYIFIAH CYVPVLSTTI PHLKKRLKLF DWKDIRCDKT 

       490        500        510        520        530        540 
GYYIIFENSR RGEEETERCF KVCHMKPLFT YIMNMESQPY GNPNYERSPS PERLQAERRE 

       550        560        570        580        590        600 
RAERERLKKE ADLDLEEEKK QRAIDLDPCR EVLALIVRDL KDKLLEDVKS RIAAPTLYDY 

       610        620        630        640        650        660 
LDPDRHAARR RALGIPDPEG IRRHTFQLDV DIFGSNNPQS SLPGGRSFSP YGLNILALPR 

       670        680        690        700        710        720 
IRKARRLNRA HAAFLDERRK QPVRRKEVRP LYHRLQQLHD VDDSDEDQRT PFSRDIDEQD 

       730        740        750        760        770        780 
SRPPSRMSSR SSISDDGEES EPLDGLASQD KRHEARLLGL EYGDSGTTLN ETVDGYSRHD 

       790        800        810        820        830        840 
SPGLSSTRKR KRLAEGIEVR KRPKEESERS ELNRSVETEN TLFYEESQHS EAAELGAVKP 

       850        860        870        880        890        900 
ENLAGIGGKF LGRLEDRSIK EDGEKENVER LQIKSAIQGA DLDVQPPLPD ESTIAKSHED 

       910        920        930        940        950        960 
PITEIEWGVS NDEPRPTVDD DETIILDLDG WQNLVKDEED LCFLRHVLDG QSRSKVGNLS 

       970        980        990       1000       1010       1020 
AWAWRQKEIK ALNRPGESGP VHQETRIPDY YVCNPTGAAR TEGRKRILES EKSKYLPHRI 

      1030       1040       1050       1060       1070       1080 
KVQKAREERE ANAKSDPHAS AAEAARISAA KTISKSTSRS TRVNNRRLVA DINAQKQALP 

      1090       1100       1110       1120       1130       1140 
MQGGDGDVLR FNQLKKRKKP VRFARSAIHN WGLYAEENIS ANDMIIEYVG EKVRQQVADM 

      1150       1160       1170       1180       1190       1200 
RERQYLKSGI GSSYLFRIDE NTVIDATKRG GIARFINHSC TPNCTAKIIK VDGSKRIVIY 

      1210       1220       1230       1240 
ALRDIGRDEE LTYDYKFERE WDSDDRIPCL CGSTGCKGFL N 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027698 Genomic DNA. Translation: EAW15850.1.
RefSeqXP_001257747.1. XM_001257746.1.

3D structure databases

ProteinModelPortalA1DM29.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING36630.CADNFIAP00004585.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00004713; CADNFIAP00004585; CADNFIAG00004713.
GeneID4584262.
KEGGnfi:NFIA_051950.

Phylogenomic databases

HOGENOMHOG000181654.
KOK11422.
OMADKTGYYI.
OrthoDBEOG7P8PH3.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
InterProIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR012677. Nucleotide-bd_a/b_plait.
IPR003616. Post-SET_dom.
IPR000504. RRM_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PfamPF11764. N-SET. 1 hit.
PF00076. RRM_1. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEPS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1DM29_NEOFI
AccessionPrimary (citable) accession number: A1DM29
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)