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A1DLJ5 (BGLE_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase E

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase E
Cellobiase E
Gentiobiase E
Gene names
Name:bglE
ORF Names:NFIA_050080
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length1045 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Cell membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentCell membrane
Membrane
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10451045Probable beta-glucosidase E
PRO_0000394875

Regions

Topological domain1 – 163163Cytoplasmic Potential
Transmembrane164 – 18421Helical; Signal-anchor for type II membrane protein; Potential
Topological domain185 – 1045861Extracellular Potential

Sites

Active site4301 By similarity

Amino acid modifications

Glycosylation2261N-linked (GlcNAc...) Potential
Glycosylation2341N-linked (GlcNAc...) Potential
Glycosylation4021N-linked (GlcNAc...) Potential
Glycosylation4731N-linked (GlcNAc...) Potential
Glycosylation5121N-linked (GlcNAc...) Potential
Glycosylation5771N-linked (GlcNAc...) Potential
Glycosylation8931N-linked (GlcNAc...) Potential
Glycosylation9021N-linked (GlcNAc...) Potential
Glycosylation9881N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1DLJ5 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 9587BF4A3DA770F8

FASTA1,045114,875
        10         20         30         40         50         60 
MAPPDSTHGG SFRDHLKTND RSSTSKGKQR YAPLHEAIPE EISSFRSPSE YADADTDSDS 

        70         80         90        100        110        120 
DHENSGSYQL RPVDRYGSHH SSAFIPVIRD DGGVETYLDS ITEAEQELLS ASKQYDLFDD 

       130        140        150        160        170        180 
DDSDDLDSDE EATLRYKLKD RLKRRRARLQ AWPPVKYARI WWRTLLAVIV TLAVVVWGFL 

       190        200        210        220        230        240 
SFAVSHREEP KVWPMVPSDS WFPSPKGGTL KHWEESYKKA QSLVRNMTLV EKVNITTGIG 

       250        260        270        280        290        300 
WQMGLCVGNT GLRFADHVSA FPAGITTGST WNRELMRERG VAMGREARLK GVNVLLGPSM 

       310        320        330        340        350        360 
GPLGMMPAGG RNWEGFGSDP VLQAVAAAET IRGIQSNGVM ATAKHFVMNE QEHFRQPFEW 

       370        380        390        400        410        420 
GIPTALSSNV GDRALHEVFA WPFAESIRAD VASVMCSYQM VNNSHACENS KLLNGILKDE 

       430        440        450        460        470        480 
LGFQGFVQSD WLAQRSGINS VLGGLDMSMP GDGLHWVDGK SLWGSELTRA VLNTSVPVER 

       490        500        510        520        530        540 
LNDMVTRIVA AWYHLGQDTW ERPPPEGNGG PNFSSWTNDK VGWLHTGSND GSYAVVNHYV 

       550        560        570        580        590        600 
DAQGTGPEAH SIIARKVAAE GTVLLKNVDR TLPLSRNASS PSGGILRVGI YGDDAGPASG 

       610        620        630        640        650        660 
PNACPDRGCN QGTLATGWGS GTVEFPYLVS PIEALESAWS TEIESTAYLR NAVMPADAVD 

       670        680        690        700        710        720 
KDLCLVFVNA DSGEGYISAG GIHGDRNDLF LQKGGDTLVR TVASNCGGGQ GKTVIVIHAV 

       730        740        750        760        770        780 
GPVVMESWID LPGVHAVLLS NLPGQESGNA LMDVLFGEVD ASGRLPYTIG KSLEDYGPGA 

       790        800        810        820        830        840 
QVLYEPNAPV PQADFLDALY IDYRHFDRYN ITPRFEFGFG LSYTTFELSD LSISPLQRKS 

       850        860        870        880        890        900 
RSPPPRPADA VAPPVYDTSL PDPASALFPT GFQPIFKYIY PYLSNLDGTA PRNYSFYPKG 

       910        920        930        940        950        960 
YNETQSPSPA GGGAGGHPAL YEEMVSVKLQ VSNTGDRKGQ EVVQLYVSFP PDVTEEGDWV 

       970        980        990       1000       1010       1020 
EVDSDADKTG EKQRERMKIE FPERVLRNFT KIELEPSERR EVQMTLSRKD LSYWSTREQN 

      1030       1040 
WVMPEGKFQI WVGRSSRDLP LMGEY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027698 Genomic DNA. Translation: EAW15666.1.
RefSeqXP_001257563.1. XM_001257562.1.

3D structure databases

ProteinModelPortalA1DLJ5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING36630.CADNFIAP00005089.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00005217; CADNFIAP00005089; CADNFIAG00005217.
GeneID4584078.
KEGGnfi:NFIA_050080.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
KOK05349.
OMAQRYAPLH.
OrthoDBEOG7HMS8F.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetSearch...

Entry information

Entry nameBGLE_NEOFI
AccessionPrimary (citable) accession number: A1DLJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries