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A1DIC0

- XLNR_NEOFI

UniProt

A1DIC0 - XLNR_NEOFI

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Protein
Xylanolytic transcriptional activator xlnR
Gene
xlnR, NFIA_090850
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi119 – 14527Zn(2)-C6 fungal-type
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. positive regulation of transcription, DNA-templated Source: UniProtKB
  2. xylan catabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Xylanolytic transcriptional activator xlnR
Alternative name(s):
Xylanase regulator
Gene namesi
Name:xlnR
ORF Names:NFIA_090850
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
ProteomesiUP000006702: Unassembled WGS sequence

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 950950Xylanolytic transcriptional activator xlnR
PRO_0000393157Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00007051.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi163 – 1697Poly-Ala

Sequence similaritiesi

Belongs to the xlnR/xlr1 family.

Phylogenomic databases

eggNOGiNOG132941.
HOGENOMiHOG000167193.
OrthoDBiEOG7380DB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1DIC0-1 [UniParc]FASTAAdd to Basket

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MSTTSLQHFS HSYSPFPSSR SSNRMAQSQT SGLDTLAEGS QYALEQLQMS    50
REAAGDGEAT NSMGKPKDQY QIDNDNHHNN HSLPSFKNSS QRDPLVEARS 100
TIRKNSASAP VRRRISRACD QCNQLRTKCD GQNPCAHCIE FGLTCEYARE 150
RKKRGKASKK DLAAAAAAAT NPGQPNGSSG KEDAAMVGGH TSPDRRPTLN 200
GRYDPAFEVP RNLNGSAQHS EASGMVGMQN SQHLPPHSQS SMGGGLEGLS 250
LNGYNGLNDS SRPSMPVPEL QSLHMLHNSH TNPRSPSSVL PHHRYNGGYN 300
DSAYSLMNPQ EPNSTSISHF RLGSSTENPP NSFLGLSPPA QSPGWLPLPS 350
PSPANFPSFS MASFSTTLRY PVLHPVLPHI ASIIPQSLAC DLLDVYFTSS 400
SSSHLSPQSP YVVGYIFRKQ SFLHPTKPRV CTPGLLASML WVAAQTSDAP 450
FLTSPPSARG RVCQKLLELT IGLLRPLIHG PAPGETSPNY AANMVINGVA 500
LGGFGVSMDQ LGAQSSATGA VDDVATYVHL ATVISASEYK AASMRWWTAA 550
WSLARELKLG RELPPNTPHS RPDAERDGDP DADLSKRHPP PLITSMGHGP 600
GNTVINITEE EREERRRLWW LLYATDRHLA LCYNRPLTLL DKECEGLLQP 650
MNDDLWQAGD FATYRQAGPP VECTGHSMFG YFLPLMTILG EIVDLQQARN 700
HPRFGLAFRN SAECEAQVLE IARQLDVYAQ SLKEFETRYT SSLALGAAET 750
EAAMEGSHLN HVSPSGRSSS TVESRVNESI VHTKMVVAYG THIMHVLHIL 800
LAGKWDPINL LDDNDLWISS ESFVAAMGHA VGAAEAASEI LEYDPDLSFM 850
PFFFGIYLLQ GSFLLLLTAD KLQGDASPSV VRACETIVRA HEACVVTLNT 900
EYQRTFRKVM RSALAQVRGR LPEDFGEQQQ RRREVLALYR WTGDGSGLAL 950
Length:950
Mass (Da):103,771
Last modified:March 23, 2010 - v2
Checksum:i606F9D26F41F36D9
GO

Sequence cautioni

The sequence EAW19127.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence EAW19127.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027696 Genomic DNA. Translation: EAW19127.1. Sequence problems.
RefSeqiXP_001261024.1. XM_001261023.1.

Genome annotation databases

GeneIDi4587582.
KEGGinfi:NFIA_090850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027696 Genomic DNA. Translation: EAW19127.1 . Sequence problems.
RefSeqi XP_001261024.1. XM_001261023.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 36630.CADNFIAP00007051.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4587582.
KEGGi nfi:NFIA_090850.

Phylogenomic databases

eggNOGi NOG132941.
HOGENOMi HOG000167193.
OrthoDBi EOG7380DB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
Pfami PF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view ]
SMARTi SM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Entry informationi

Entry nameiXLNR_NEOFI
AccessioniPrimary (citable) accession number: A1DIC0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: April 16, 2014
This is version 38 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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