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A1DIC0

- XLNR_NEOFI

UniProt

A1DIC0 - XLNR_NEOFI

Protein

Xylanolytic transcriptional activator xlnR

Gene

xlnR

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 2 (23 Mar 2010)
      Previous versions | rss
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    Functioni

    Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi119 – 14527Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. positive regulation of transcription, DNA-templated Source: UniProtKB
    2. xylan catabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylanolytic transcriptional activator xlnR
    Alternative name(s):
    Xylanase regulator
    Gene namesi
    Name:xlnR
    ORF Names:NFIA_090850
    OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
    Taxonomic identifieri331117 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
    ProteomesiUP000006702: Unassembled WGS sequence

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 950950Xylanolytic transcriptional activator xlnRPRO_0000393157Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi36630.CADNFIAP00007051.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi163 – 1697Poly-Ala

    Sequence similaritiesi

    Belongs to the xlnR/xlr1 family.Curated
    Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG132941.
    HOGENOMiHOG000167193.
    OrthoDBiEOG7380DB.

    Family and domain databases

    Gene3Di4.10.240.10. 1 hit.
    InterProiIPR007219. Transcription_factor_dom_fun.
    IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view]
    PfamiPF04082. Fungal_trans. 1 hit.
    PF00172. Zn_clus. 1 hit.
    [Graphical view]
    SMARTiSM00906. Fungal_trans. 1 hit.
    SM00066. GAL4. 1 hit.
    [Graphical view]
    SUPFAMiSSF57701. SSF57701. 1 hit.
    PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1DIC0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTTSLQHFS HSYSPFPSSR SSNRMAQSQT SGLDTLAEGS QYALEQLQMS    50
    REAAGDGEAT NSMGKPKDQY QIDNDNHHNN HSLPSFKNSS QRDPLVEARS 100
    TIRKNSASAP VRRRISRACD QCNQLRTKCD GQNPCAHCIE FGLTCEYARE 150
    RKKRGKASKK DLAAAAAAAT NPGQPNGSSG KEDAAMVGGH TSPDRRPTLN 200
    GRYDPAFEVP RNLNGSAQHS EASGMVGMQN SQHLPPHSQS SMGGGLEGLS 250
    LNGYNGLNDS SRPSMPVPEL QSLHMLHNSH TNPRSPSSVL PHHRYNGGYN 300
    DSAYSLMNPQ EPNSTSISHF RLGSSTENPP NSFLGLSPPA QSPGWLPLPS 350
    PSPANFPSFS MASFSTTLRY PVLHPVLPHI ASIIPQSLAC DLLDVYFTSS 400
    SSSHLSPQSP YVVGYIFRKQ SFLHPTKPRV CTPGLLASML WVAAQTSDAP 450
    FLTSPPSARG RVCQKLLELT IGLLRPLIHG PAPGETSPNY AANMVINGVA 500
    LGGFGVSMDQ LGAQSSATGA VDDVATYVHL ATVISASEYK AASMRWWTAA 550
    WSLARELKLG RELPPNTPHS RPDAERDGDP DADLSKRHPP PLITSMGHGP 600
    GNTVINITEE EREERRRLWW LLYATDRHLA LCYNRPLTLL DKECEGLLQP 650
    MNDDLWQAGD FATYRQAGPP VECTGHSMFG YFLPLMTILG EIVDLQQARN 700
    HPRFGLAFRN SAECEAQVLE IARQLDVYAQ SLKEFETRYT SSLALGAAET 750
    EAAMEGSHLN HVSPSGRSSS TVESRVNESI VHTKMVVAYG THIMHVLHIL 800
    LAGKWDPINL LDDNDLWISS ESFVAAMGHA VGAAEAASEI LEYDPDLSFM 850
    PFFFGIYLLQ GSFLLLLTAD KLQGDASPSV VRACETIVRA HEACVVTLNT 900
    EYQRTFRKVM RSALAQVRGR LPEDFGEQQQ RRREVLALYR WTGDGSGLAL 950
    Length:950
    Mass (Da):103,771
    Last modified:March 23, 2010 - v2
    Checksum:i606F9D26F41F36D9
    GO

    Sequence cautioni

    The sequence EAW19127.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence EAW19127.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW19127.1. Sequence problems.
    RefSeqiXP_001261024.1. XM_001261023.1.

    Genome annotation databases

    GeneIDi4587582.
    KEGGinfi:NFIA_090850.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW19127.1 . Sequence problems.
    RefSeqi XP_001261024.1. XM_001261023.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36630.CADNFIAP00007051.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4587582.
    KEGGi nfi:NFIA_090850.

    Phylogenomic databases

    eggNOGi NOG132941.
    HOGENOMi HOG000167193.
    OrthoDBi EOG7380DB.

    Family and domain databases

    Gene3Di 4.10.240.10. 1 hit.
    InterProi IPR007219. Transcription_factor_dom_fun.
    IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view ]
    Pfami PF04082. Fungal_trans. 1 hit.
    PF00172. Zn_clus. 1 hit.
    [Graphical view ]
    SMARTi SM00906. Fungal_trans. 1 hit.
    SM00066. GAL4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57701. SSF57701. 1 hit.
    PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

    Entry informationi

    Entry nameiXLNR_NEOFI
    AccessioniPrimary (citable) accession number: A1DIC0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 23, 2010
    Last sequence update: March 23, 2010
    Last modified: October 1, 2014
    This is version 39 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3