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A1DIC0

- XLNR_NEOFI

UniProt

A1DIC0 - XLNR_NEOFI

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Protein

Xylanolytic transcriptional activator xlnR

Gene

xlnR

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi119 – 14527Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. positive regulation of transcription, DNA-templated Source: UniProtKB
  2. xylan catabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Xylanolytic transcriptional activator xlnR
Alternative name(s):
Xylanase regulator
Gene namesi
Name:xlnR
ORF Names:NFIA_090850
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
ProteomesiUP000006702: Unassembled WGS sequence

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 950950Xylanolytic transcriptional activator xlnRPRO_0000393157Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00007051.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi163 – 1697Poly-Ala

Sequence similaritiesi

Belongs to the xlnR/xlr1 family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG132941.
HOGENOMiHOG000167193.
OrthoDBiEOG7380DB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1DIC0-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSTTSLQHFS HSYSPFPSSR SSNRMAQSQT SGLDTLAEGS QYALEQLQMS
60 70 80 90 100
REAAGDGEAT NSMGKPKDQY QIDNDNHHNN HSLPSFKNSS QRDPLVEARS
110 120 130 140 150
TIRKNSASAP VRRRISRACD QCNQLRTKCD GQNPCAHCIE FGLTCEYARE
160 170 180 190 200
RKKRGKASKK DLAAAAAAAT NPGQPNGSSG KEDAAMVGGH TSPDRRPTLN
210 220 230 240 250
GRYDPAFEVP RNLNGSAQHS EASGMVGMQN SQHLPPHSQS SMGGGLEGLS
260 270 280 290 300
LNGYNGLNDS SRPSMPVPEL QSLHMLHNSH TNPRSPSSVL PHHRYNGGYN
310 320 330 340 350
DSAYSLMNPQ EPNSTSISHF RLGSSTENPP NSFLGLSPPA QSPGWLPLPS
360 370 380 390 400
PSPANFPSFS MASFSTTLRY PVLHPVLPHI ASIIPQSLAC DLLDVYFTSS
410 420 430 440 450
SSSHLSPQSP YVVGYIFRKQ SFLHPTKPRV CTPGLLASML WVAAQTSDAP
460 470 480 490 500
FLTSPPSARG RVCQKLLELT IGLLRPLIHG PAPGETSPNY AANMVINGVA
510 520 530 540 550
LGGFGVSMDQ LGAQSSATGA VDDVATYVHL ATVISASEYK AASMRWWTAA
560 570 580 590 600
WSLARELKLG RELPPNTPHS RPDAERDGDP DADLSKRHPP PLITSMGHGP
610 620 630 640 650
GNTVINITEE EREERRRLWW LLYATDRHLA LCYNRPLTLL DKECEGLLQP
660 670 680 690 700
MNDDLWQAGD FATYRQAGPP VECTGHSMFG YFLPLMTILG EIVDLQQARN
710 720 730 740 750
HPRFGLAFRN SAECEAQVLE IARQLDVYAQ SLKEFETRYT SSLALGAAET
760 770 780 790 800
EAAMEGSHLN HVSPSGRSSS TVESRVNESI VHTKMVVAYG THIMHVLHIL
810 820 830 840 850
LAGKWDPINL LDDNDLWISS ESFVAAMGHA VGAAEAASEI LEYDPDLSFM
860 870 880 890 900
PFFFGIYLLQ GSFLLLLTAD KLQGDASPSV VRACETIVRA HEACVVTLNT
910 920 930 940 950
EYQRTFRKVM RSALAQVRGR LPEDFGEQQQ RRREVLALYR WTGDGSGLAL
Length:950
Mass (Da):103,771
Last modified:March 23, 2010 - v2
Checksum:i606F9D26F41F36D9
GO

Sequence cautioni

The sequence EAW19127.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence EAW19127.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027696 Genomic DNA. Translation: EAW19127.1. Sequence problems.
RefSeqiXP_001261024.1. XM_001261023.1.

Genome annotation databases

GeneIDi4587582.
KEGGinfi:NFIA_090850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027696 Genomic DNA. Translation: EAW19127.1 . Sequence problems.
RefSeqi XP_001261024.1. XM_001261023.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 36630.CADNFIAP00007051.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4587582.
KEGGi nfi:NFIA_090850.

Phylogenomic databases

eggNOGi NOG132941.
HOGENOMi HOG000167193.
OrthoDBi EOG7380DB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
Pfami PF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view ]
SMARTi SM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Entry informationi

Entry nameiXLNR_NEOFI
AccessioniPrimary (citable) accession number: A1DIC0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: October 29, 2014
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3