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A1DHY9 (EGLX_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable endo-1,3(4)-beta-glucanase NFIA_089530

EC=3.2.1.6
Alternative name(s):
Mixed-linked glucanase NFIA_089530
Gene names
ORF Names:NFIA_089530
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length651 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates By similarity.

Catalytic activity

Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.

Subcellular location

Cell membrane; Lipid-anchorGPI-anchor By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 629608Probable endo-1,3(4)-beta-glucanase NFIA_089530
PRO_0000395095
Propeptide630 – 65122Removed in mature form Potential
PRO_0000395096

Regions

Compositional bias332 – 506175Ala-rich

Sites

Active site1451Nucleophile By similarity
Active site1501Proton donor By similarity

Amino acid modifications

Lipidation6291GPI-anchor amidated asparagine Potential
Glycosylation641N-linked (GlcNAc...) Potential
Glycosylation2001N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1DHY9 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 0DD6CA7D45C885A8

FASTA65166,035
        10         20         30         40         50         60 
MAPSSLFLSV GSLIASSLVS ATALEARQSQ TYQLAESWQG ESFINDWNFF DRADPTNGYV 

        70         80         90        100        110        120 
TYVNQSFAEQ SGLVKVTQSG SFYMGVDYES TLNPNGPGRE SVRIETKNYY TEGLYVIDIE 

       130        140        150        160        170        180 
HMPGSICGTW PAFWSVGKDW PNDGEIDIIE GVNLQKANKI VLHTSGSCDV SGSNDMTGTL 

       190        200        210        220        230        240 
SSSECGEASG TVGCVVKGTN GSSGDPFNEA GGGVYAMEWT DTFIKIWFFP RSQIPASLSS 

       250        260        270        280        290        300 
GNPDTSSFGT PMAHLQGSCD FAERFKAQKF IIDTTFCGDW AGNVFAESTC PMSDPSSPMQ 

       310        320        330        340        350        360 
SCVNYVAQNP AAFKEAYWEI NSIKVYQYGV SAASSAAVSQ ATASKVEGTL VSVQAANTAT 

       370        380        390        400        410        420 
PTVPVPAETT AVPQPAQTNT VATSAADYAT QSSAETTTVP AATGAPSVSA AEGGDSELES 

       430        440        450        460        470        480 
TSTVYVTSTT TICPVAESSS AAAAGGKKDA PFNGVSGAEV AATSVAAAPA AATSEHPGAD 

       490        500        510        520        530        540 
AIANSAAATS TVAKSEGVAS QLTAGALSEI PTAPPEPVSQ AVSTGSFDDS DTAQGDSEEH 

       550        560        570        580        590        600 
GSIASASAAP STIPVPASSS AAALGGSSIA SSFASSRLVP RPTGSSTAAS VTAIATWSPT 

       610        620        630        640        650 
AGERASGTAK GSATLTAPSE VVFTPGLSNG ANRMSVGLSG LIGVMFIAAL A 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW18996.1.
RefSeqXP_001260893.1. XM_001260892.1.

3D structure databases

ProteinModelPortalA1DHY9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00007993; CADNFIAP00007826; CADNFIAG00007993.
GeneID4587451.
KEGGnfi:NFIA_089530.

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000166269.
OMASCVNYVA.
OrthoDBEOG7HB5KN.

Family and domain databases

Gene3D2.60.120.200. 2 hits.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
[Graphical view]
PfamPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 2 hits.
ProtoNetSearch...

Entry information

Entry nameEGLX_NEOFI
AccessionPrimary (citable) accession number: A1DHY9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries