A1DHW8 (ABNB_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable arabinan endo-1,5-alpha-L-arabinosidase B
EC=3.2.1.99

Alternative name(s):
Endo-1,5-alpha-L-arabinanase B
Short name=ABN B

Gene names

Name:	abnB
ORF Names:	NFIA_089320

Organism

Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]

Taxonomic identifier

331117 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Neosartorya › Neosartorya fischeri group › Neosartorya fischeri

Protein attributes

Sequence length	372 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan By similarity.
Catalytic activity	Endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5)-arabinans.
Pathway	Glycan metabolism; L-arabinan degradation.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 43 family.
Sequence caution	The sequence EAW18975.1 differs from that shown. Reason: Frameshift at positions 353 and 357.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Polysaccharide degradation Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arabinan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	arabinan endo-1,5-alpha-L-arabinosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 372	356	Probable arabinan endo-1,5-alpha-L-arabinosidase B		PRO_0000394631
Amino acid modifications
	Glycosylation	363	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	A1DHW8 [UniParc]. Last modified June 15, 2010. Version 2. Checksum: B1E2FB8A6B1D2C54	FASTA	372	41,116
	10 20 30 40 50 60 MAVLVALFCL VTWALCTRIP QYSTQGTQQL QQPEKTPHPH PRPEDPFPPT HAADFKIHDP 70 80 90 100 110 120 SIIHVDGTYY SYSVGKHIRI HQAPSLDGPW KRTGTVLDAD SVIPKGDRKA PWAPQTVHHG 130 140 150 160 170 180 DTYYCFYAVS NSGCRDSAIG VATSKSPGPG GWTDHGLLVQ SGTGKGSDEH PFASSNTIDP 190 200 210 220 230 240 SVFVGEDGHG YLMFGSFWSG IWQVPLDETL LSVAGDTRSE ARQLVYMEKA PLPASKHPNP 250 260 270 280 290 300 LCREPSGARP IEGSFLSYHE PWYYLWFSYG KCCKFDTKNL PPPGREYSIR VGRSKSPRGP 310 320 330 340 350 360 FVDKQGRDLA NGGGEIVYAS NRDVYAPGGQ AVLTEKSGDI LYYHYCRYPA VQETEVDADL 370 TVNKSTSYDF WV

References

[1]

"Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus." Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M. , Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., Jiang B., Denning D.W., Nierman W.C. PLoS Genet. 4:E1000046-E1000046(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS027696 Genomic DNA. Translation: EAW18975.1. Frameshift.
RefSeq	XP_001260872.1. XM_001260871.1.
3D structure databases
ProteinModelPortal	A1DHW8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADNFIAT00008280; CADNFIAP00008113; CADNFIAG00008280.
GeneID	4587430.
KEGG	nfi:NFIA_089320.
Phylogenomic databases
eggNOG	COG3507.
OrthoDB	EOG4N605Q.
Enzyme and pathway databases
UniPathway	UPA00667.
Family and domain databases
Gene3D	2.115.10.20. 1 hit.
InterPro	IPR006710. Glyco_hydro_43. IPR016840. Glyco_hydro_43_endo_a_Ara-ase. IPR023296. Glyco_hydro_beta-prop. [Graphical view]
PANTHER	PTHR22925. PTHR22925. 1 hit.
Pfam	PF04616. Glyco_hydro_43. 1 hit. [Graphical view]
PIRSF	PIRSF026534. Endo_alpha-L-arabinosidase. 1 hit.
SUPFAM	SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ABNB_NEOFI

Accession

Primary (citable) accession number: A1DHW8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	March 6, 2013
This is version 34 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program