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A1DHW6 (SCONB_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene names
Name:sconB
ORF Names:NFIA_089300
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor By similarity.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Component of the SCF(sconB) E3 ubiquitin ligase complex By similarity.

Sequence similarities

Belongs to the WD repeat MET30/SCONB/SCON-2 family.

Contains 1 F-box domain.

Contains 7 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 689689Probable E3 ubiquitin ligase complex SCF subunit sconB
PRO_0000397253

Regions

Domain186 – 23247F-box
Repeat358 – 39538WD 1
Repeat398 – 43740WD 2
Repeat439 – 47537WD 3
Repeat477 – 51842WD 4
Repeat572 – 61544WD 5
Repeat616 – 65540WD 6
Repeat658 – 68932WD 7

Sequences

Sequence LengthMass (Da)Tools
A1DHW6 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: B87ACA25A35F4994

FASTA68977,242
        10         20         30         40         50         60 
MDAHELSFRD GHGSSTSTMK DECASEEKAL YLPGDSSFAS VFGPSETVED VETGPESTQD 

        70         80         90        100        110        120 
KPHSFNTQKP IREKLAGKNV APFLARHIPE QYAPLGSQTG QPVEISSANS KYCYRHRPDL 

       130        140        150        160        170        180 
KCRRQADEPT MDKLQRSDQQ GIAHAWSIFS AAPAKHRKLI LQGIMAQCCF PQLSFISATV 

       190        200        210        220        230        240 
RDLIRIDFLT ALPPEISFKI LCYLDTTSLC KAAQVSRRWR ALADDDVVWH RMCEQHIHRK 

       250        260        270        280        290        300 
CKKCGWGLPL LDRKRLRESK REIERRAATW DVSEQPAETE SNSATIDTAA SGSKRKPESD 

       310        320        330        340        350        360 
KEDTAMVKRQ CTSIVSQSEQ NEDYFKTRYR PWKEVYKDRF KVGTNWKYGR CSIRVFKGHS 

       370        380        390        400        410        420 
NGIMCLQFED NILATGSYDA TIKIWDTETG EELRTLKGHR SGIRCLQFDD TKLISGSMDH 

       430        440        450        460        470        480 
TLKVWNWRTG ECISTYSGHR GGVVGLHFDA TILASGSVDK TVKIWNFEDK STCLLRGHTD 

       490        500        510        520        530        540 
WVNAVRVDSA SRTVFSASDD CTVKLWDLDT KSCIRTFHGH VGQVQQVVPL PREFEFEDHD 

       550        560        570        580        590        600 
VECENDNVSV TSGDSPAASP QAIPGFDAQT SDTPSSAFGP AFDDGRPSPP RYIVTSALDS 

       610        620        630        640        650        660 
TIRLWETSSG RCLRTFFGHL EGVWALAADT LRIVSGAEDR MVKIWDPRTG KCERTFTGHS 

       670        680 
GPVTCIGLGD SRFATGSEDC EVRMYSFQT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW18973.1.
RefSeqXP_001260870.1. XM_001260869.1.

3D structure databases

ProteinModelPortalA1DHW6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING36630.CADNFIAP00006688.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00006855; CADNFIAP00006688; CADNFIAG00006855.
GeneID4587428.
KEGGnfi:NFIA_089300.

Phylogenomic databases

eggNOGCOG2319.
HOGENOMHOG000166480.
KOK10259.
OMAMCLQFSE.
OrthoDBEOG7C5MHX.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D2.130.10.10. 3 hits.
InterProIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR011047. Quinonprotein_ADH-like_supfam.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMSSF50998. SSF50998. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCONB_NEOFI
AccessionPrimary (citable) accession number: A1DHW6
Entry history
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways