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A1DHW6

- SCONB_NEOFI

UniProt

A1DHW6 - SCONB_NEOFI

Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

    Pathwayi

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation, Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable E3 ubiquitin ligase complex SCF subunit sconB
    Alternative name(s):
    Sulfur controller B
    Sulfur metabolite repression control protein B
    Gene namesi
    Name:sconB
    ORF Names:NFIA_089300
    OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
    Taxonomic identifieri331117 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
    ProteomesiUP000006702: Unassembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 689689Probable E3 ubiquitin ligase complex SCF subunit sconBPRO_0000397253Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

    Protein-protein interaction databases

    STRINGi36630.CADNFIAP00006688.

    Structurei

    3D structure databases

    ProteinModelPortaliA1DHW6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini186 – 23247F-boxPROSITE-ProRule annotationAdd
    BLAST
    Repeati358 – 39538WD 1Add
    BLAST
    Repeati398 – 43740WD 2Add
    BLAST
    Repeati439 – 47537WD 3Add
    BLAST
    Repeati477 – 51842WD 4Add
    BLAST
    Repeati572 – 61544WD 5Add
    BLAST
    Repeati616 – 65540WD 6Add
    BLAST
    Repeati658 – 68932WD 7Add
    BLAST

    Sequence similaritiesi

    Contains 1 F-box domain.PROSITE-ProRule annotation
    Contains 7 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    eggNOGiCOG2319.
    HOGENOMiHOG000166480.
    KOiK10259.
    OMAiMCLQFSE.
    OrthoDBiEOG7C5MHX.

    Family and domain databases

    Gene3Di2.130.10.10. 3 hits.
    InterProiIPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR011047. Quinonprotein_ADH-like_supfam.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50998. SSF50998. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEiPS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1DHW6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAHELSFRD GHGSSTSTMK DECASEEKAL YLPGDSSFAS VFGPSETVED    50
    VETGPESTQD KPHSFNTQKP IREKLAGKNV APFLARHIPE QYAPLGSQTG 100
    QPVEISSANS KYCYRHRPDL KCRRQADEPT MDKLQRSDQQ GIAHAWSIFS 150
    AAPAKHRKLI LQGIMAQCCF PQLSFISATV RDLIRIDFLT ALPPEISFKI 200
    LCYLDTTSLC KAAQVSRRWR ALADDDVVWH RMCEQHIHRK CKKCGWGLPL 250
    LDRKRLRESK REIERRAATW DVSEQPAETE SNSATIDTAA SGSKRKPESD 300
    KEDTAMVKRQ CTSIVSQSEQ NEDYFKTRYR PWKEVYKDRF KVGTNWKYGR 350
    CSIRVFKGHS NGIMCLQFED NILATGSYDA TIKIWDTETG EELRTLKGHR 400
    SGIRCLQFDD TKLISGSMDH TLKVWNWRTG ECISTYSGHR GGVVGLHFDA 450
    TILASGSVDK TVKIWNFEDK STCLLRGHTD WVNAVRVDSA SRTVFSASDD 500
    CTVKLWDLDT KSCIRTFHGH VGQVQQVVPL PREFEFEDHD VECENDNVSV 550
    TSGDSPAASP QAIPGFDAQT SDTPSSAFGP AFDDGRPSPP RYIVTSALDS 600
    TIRLWETSSG RCLRTFFGHL EGVWALAADT LRIVSGAEDR MVKIWDPRTG 650
    KCERTFTGHS GPVTCIGLGD SRFATGSEDC EVRMYSFQT 689
    Length:689
    Mass (Da):77,242
    Last modified:January 23, 2007 - v1
    Checksum:iB87ACA25A35F4994
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW18973.1.
    RefSeqiXP_001260870.1. XM_001260869.1.

    Genome annotation databases

    EnsemblFungiiCADNFIAT00006855; CADNFIAP00006688; CADNFIAG00006855.
    GeneIDi4587428.
    KEGGinfi:NFIA_089300.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW18973.1 .
    RefSeqi XP_001260870.1. XM_001260869.1.

    3D structure databases

    ProteinModelPortali A1DHW6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36630.CADNFIAP00006688.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADNFIAT00006855 ; CADNFIAP00006688 ; CADNFIAG00006855 .
    GeneIDi 4587428.
    KEGGi nfi:NFIA_089300.

    Phylogenomic databases

    eggNOGi COG2319.
    HOGENOMi HOG000166480.
    KOi K10259.
    OMAi MCLQFSE.
    OrthoDBi EOG7C5MHX.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Family and domain databases

    Gene3Di 2.130.10.10. 3 hits.
    InterProi IPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR011047. Quinonprotein_ADH-like_supfam.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50998. SSF50998. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEi PS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

    Entry informationi

    Entry nameiSCONB_NEOFI
    AccessioniPrimary (citable) accession number: A1DHW6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 10, 2010
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3