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A1DGM6 (EXGB_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucan endo-1,6-beta-glucosidase B

EC=3.2.1.75
Alternative name(s):
Beta-1,6-glucanase B
Endo-1,6-beta-D-glucanase B
Endo-1,6-beta-glucanase B
Gene names
Name:exgB
ORF Names:NFIA_084850
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides By similarity.

Catalytic activity

Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpolysaccharide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucan endo-1,6-beta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 400383Probable glucan endo-1,6-beta-glucosidase B
PRO_0000394711

Sites

Active site2191Proton donor By similarity
Active site3201Nucleophile By similarity

Amino acid modifications

Glycosylation301N-linked (GlcNAc...) Potential
Glycosylation2721N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1DGM6 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: F95C0A9E0C957F8A

FASTA40044,823
        10         20         30         40         50         60 
MIRRLAALSA LSGLATAWLP EVNKKITSTN GTNLFSSSNG KIRGVNLGSQ FVFEPWIAEK 

        70         80         90        100        110        120 
AWSDMGCGGQ KSEFDCVSSL GQAKANGAFA SHWGSWITQD DLAEMVSYGL NTIRVPVGYW 

       130        140        150        160        170        180 
MREDLVYSDS EHFPQGGLQY LENLCGWASD AGLYIIIDLH GAPGAQTPQN PFTGQYAPTA 

       190        200        210        220        230        240 
GFYQDYQFER ALKFLEWMTT NIHQNDKFRN VGMLEVVNEP VQDAGKVGSM RSTYYPNAFK 

       250        260        270        280        290        300 
RIRAAEQSLN IDRNNYLHIQ MMDRLWGSGD PNESLTDTYY AAYDDHRYLK WAGVAVSKDS 

       310        320        330        340        350        360 
YISTSCSDQL NSNTPTIVGE WSLSVPDSVQ WNSDWAPDSN KDFYKKWFAA QVTAYEKQQG 

       370        380        390        400 
WIFWTWKAQL GDYRWSYQDA VAAGVIPTDL NSLAGLKVCG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW18533.1.
RefSeqXP_001260430.1. XM_001260429.1.

3D structure databases

ProteinModelPortalA1DGM6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00007715; CADNFIAP00007548; CADNFIAG00007715.
GeneID4586988.
KEGGnfi:NFIA_084850.

Phylogenomic databases

eggNOGCOG2730.
HOGENOMHOG000217590.
OMASEHFPQG.
OrthoDBEOG776T0C.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEXGB_NEOFI
AccessionPrimary (citable) accession number: A1DGM6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries