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A1DG01

- ACUK_NEOFI

UniProt

A1DG01 - ACUK_NEOFI

Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi65 – 9329Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Gluconeogenesis, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription activator of gluconeogenesis acuK
    Gene namesi
    Name:acuK
    ORF Names:AN7468
    OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
    Taxonomic identifieri331117 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
    ProteomesiUP000006702: Unassembled WGS sequence

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 683683Transcription activator of gluconeogenesis acuKPRO_0000406442Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi36630.CADNFIAP00007576.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ERT1/acuK family.Curated
    Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG39365.
    HOGENOMiHOG000162694.
    OMAiLGHMSSG.
    OrthoDBiEOG70KGZB.

    Family and domain databases

    Gene3Di4.10.240.10. 1 hit.
    InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view]
    SMARTiSM00066. GAL4. 1 hit.
    [Graphical view]
    SUPFAMiSSF57701. SSF57701. 1 hit.
    PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1DG01-1 [UniParc]FASTAAdd to Basket

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    MKTEDNGSAP ALAGDHGGVD QDTPDAGDRT EQAKHKTNGT TEKAPKSSNA    50
    KDPSRPRRKK ARRACFACQR AHLTCGDERP CQRCIKRGLQ DACHDGVRKK 100
    AKYLHDAPDG ALMPGVGGNF YNNAMRNNLP LSRNGATTVN TTSQQNSGSS 150
    YYPTPQSNSY NVYQDTPLTQ NSFPSQSPVS PTFNMKTTPT ARSNSLSSSV 200
    NQQPPNTTVS GATQSQNPFA GPFFDPSDPA LFNFDLSSMN FENRYGALEF 250
    GMLGHMATGA GDSPTDSATQ RGSMGRSGST QYSTTPITGA PGFGESPGNQ 300
    QPFMFGNDPL LNEWPNSQAP NQGHLNVSGV YPQGGMMHMA KSDAPHAFAI 350
    ESGPASFSSP SATTSPHINS GYDESSLSNT VVNKSNGLTA NGQRPAITTP 400
    SLKHQSLQFG VKRRQRNPST VYESVKEPYA YTNRFHNLTA FIQRRFSPQK 450
    TLQIAKALAS IRPSFIATTK TLNRDDLIFM EKCFQRTLWE YEDFINACGT 500
    PTIVCRRTGE IAAVGKEFSI LTGWKKDVLL GKEPNLNVNT GGSSAPGSGT 550
    TSRGSFTPRS STLENATPGR PQPVFLAELL DDDSVVEFYE DFARLAFGDS 600
    RGSVMTTCKL LKYKTKEDME LAQSDDNQRW NNHLRKGGIA GEAGMNQLGF 650
    KDGKVECAYC WTVKRDVFDI PMLIVMNVSC QCF 683
    Length:683
    Mass (Da):74,236
    Last modified:January 23, 2007 - v1
    Checksum:i1DD243D44C14C210
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW18308.1.
    RefSeqiXP_001260205.1. XM_001260204.1.

    Genome annotation databases

    EnsemblFungiiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
    GeneIDi4586762.
    KEGGinfi:NFIA_082550.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW18308.1 .
    RefSeqi XP_001260205.1. XM_001260204.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36630.CADNFIAP00007576.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADNFIAT00007743 ; CADNFIAP00007576 ; CADNFIAG00007743 .
    GeneIDi 4586762.
    KEGGi nfi:NFIA_082550.

    Phylogenomic databases

    eggNOGi NOG39365.
    HOGENOMi HOG000162694.
    OMAi LGHMSSG.
    OrthoDBi EOG70KGZB.

    Family and domain databases

    Gene3Di 4.10.240.10. 1 hit.
    InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view ]
    SMARTi SM00066. GAL4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57701. SSF57701. 1 hit.
    PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

    Entry informationi

    Entry nameiACUK_NEOFI
    AccessioniPrimary (citable) accession number: A1DG01
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 5, 2011
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3