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Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi65 – 9329Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
ProteomesiUP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_082550.

Subcellular locationi

  1. Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 683683Transcription activator of gluconeogenesis acuKPRO_0000406442Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00007576.

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG39365.
HOGENOMiHOG000162694.
OMAiLGHMSSG.
OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1DG01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTEDNGSAP ALAGDHGGVD QDTPDAGDRT EQAKHKTNGT TEKAPKSSNA
60 70 80 90 100
KDPSRPRRKK ARRACFACQR AHLTCGDERP CQRCIKRGLQ DACHDGVRKK
110 120 130 140 150
AKYLHDAPDG ALMPGVGGNF YNNAMRNNLP LSRNGATTVN TTSQQNSGSS
160 170 180 190 200
YYPTPQSNSY NVYQDTPLTQ NSFPSQSPVS PTFNMKTTPT ARSNSLSSSV
210 220 230 240 250
NQQPPNTTVS GATQSQNPFA GPFFDPSDPA LFNFDLSSMN FENRYGALEF
260 270 280 290 300
GMLGHMATGA GDSPTDSATQ RGSMGRSGST QYSTTPITGA PGFGESPGNQ
310 320 330 340 350
QPFMFGNDPL LNEWPNSQAP NQGHLNVSGV YPQGGMMHMA KSDAPHAFAI
360 370 380 390 400
ESGPASFSSP SATTSPHINS GYDESSLSNT VVNKSNGLTA NGQRPAITTP
410 420 430 440 450
SLKHQSLQFG VKRRQRNPST VYESVKEPYA YTNRFHNLTA FIQRRFSPQK
460 470 480 490 500
TLQIAKALAS IRPSFIATTK TLNRDDLIFM EKCFQRTLWE YEDFINACGT
510 520 530 540 550
PTIVCRRTGE IAAVGKEFSI LTGWKKDVLL GKEPNLNVNT GGSSAPGSGT
560 570 580 590 600
TSRGSFTPRS STLENATPGR PQPVFLAELL DDDSVVEFYE DFARLAFGDS
610 620 630 640 650
RGSVMTTCKL LKYKTKEDME LAQSDDNQRW NNHLRKGGIA GEAGMNQLGF
660 670 680
KDGKVECAYC WTVKRDVFDI PMLIVMNVSC QCF
Length:683
Mass (Da):74,236
Last modified:January 23, 2007 - v1
Checksum:i1DD243D44C14C210
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027696 Genomic DNA. Translation: EAW18308.1.
RefSeqiXP_001260205.1. XM_001260204.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
GeneIDi4586762.
KEGGinfi:NFIA_082550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027696 Genomic DNA. Translation: EAW18308.1.
RefSeqiXP_001260205.1. XM_001260204.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi36630.CADNFIAP00007576.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
GeneIDi4586762.
KEGGinfi:NFIA_082550.

Organism-specific databases

EuPathDBiFungiDB:NFIA_082550.

Phylogenomic databases

eggNOGiNOG39365.
HOGENOMiHOG000162694.
OMAiLGHMSSG.
OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Entry informationi

Entry nameiACUK_NEOFI
AccessioniPrimary (citable) accession number: A1DG01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 23, 2007
Last modified: April 29, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.