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Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi65 – 93Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processGluconeogenesis, Transcription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_082550.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004064421 – 683Transcription activator of gluconeogenesis acuKAdd BLAST683

Structurei

3D structure databases

SMRiA1DG01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated

Phylogenomic databases

HOGENOMiHOG000162694.
OMAiGLPHAYA.
OrthoDBiEOG092C2QST.

Family and domain databases

CDDicd00067. GAL4. 1 hit.
Gene3Di4.10.240.10. 1 hit.
InterProiView protein in InterPro
IPR001138. Zn2-C6_fun-type_DNA-bd.
SMARTiView protein in SMART
SM00066. GAL4. 1 hit.
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiView protein in PROSITE
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A1DG01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTEDNGSAP ALAGDHGGVD QDTPDAGDRT EQAKHKTNGT TEKAPKSSNA
60 70 80 90 100
KDPSRPRRKK ARRACFACQR AHLTCGDERP CQRCIKRGLQ DACHDGVRKK
110 120 130 140 150
AKYLHDAPDG ALMPGVGGNF YNNAMRNNLP LSRNGATTVN TTSQQNSGSS
160 170 180 190 200
YYPTPQSNSY NVYQDTPLTQ NSFPSQSPVS PTFNMKTTPT ARSNSLSSSV
210 220 230 240 250
NQQPPNTTVS GATQSQNPFA GPFFDPSDPA LFNFDLSSMN FENRYGALEF
260 270 280 290 300
GMLGHMATGA GDSPTDSATQ RGSMGRSGST QYSTTPITGA PGFGESPGNQ
310 320 330 340 350
QPFMFGNDPL LNEWPNSQAP NQGHLNVSGV YPQGGMMHMA KSDAPHAFAI
360 370 380 390 400
ESGPASFSSP SATTSPHINS GYDESSLSNT VVNKSNGLTA NGQRPAITTP
410 420 430 440 450
SLKHQSLQFG VKRRQRNPST VYESVKEPYA YTNRFHNLTA FIQRRFSPQK
460 470 480 490 500
TLQIAKALAS IRPSFIATTK TLNRDDLIFM EKCFQRTLWE YEDFINACGT
510 520 530 540 550
PTIVCRRTGE IAAVGKEFSI LTGWKKDVLL GKEPNLNVNT GGSSAPGSGT
560 570 580 590 600
TSRGSFTPRS STLENATPGR PQPVFLAELL DDDSVVEFYE DFARLAFGDS
610 620 630 640 650
RGSVMTTCKL LKYKTKEDME LAQSDDNQRW NNHLRKGGIA GEAGMNQLGF
660 670 680
KDGKVECAYC WTVKRDVFDI PMLIVMNVSC QCF
Length:683
Mass (Da):74,236
Last modified:January 23, 2007 - v1
Checksum:i1DD243D44C14C210
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027696 Genomic DNA. Translation: EAW18308.1.
RefSeqiXP_001260205.1. XM_001260204.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
GeneIDi4586762.
KEGGinfi:NFIA_082550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027696 Genomic DNA. Translation: EAW18308.1.
RefSeqiXP_001260205.1. XM_001260204.1.

3D structure databases

SMRiA1DG01.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
GeneIDi4586762.
KEGGinfi:NFIA_082550.

Organism-specific databases

EuPathDBiFungiDB:NFIA_082550.

Phylogenomic databases

HOGENOMiHOG000162694.
OMAiGLPHAYA.
OrthoDBiEOG092C2QST.

Family and domain databases

CDDicd00067. GAL4. 1 hit.
Gene3Di4.10.240.10. 1 hit.
InterProiView protein in InterPro
IPR001138. Zn2-C6_fun-type_DNA-bd.
SMARTiView protein in SMART
SM00066. GAL4. 1 hit.
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiView protein in PROSITE
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiACUK_NEOFI
AccessioniPrimary (citable) accession number: A1DG01
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 23, 2007
Last modified: June 7, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.