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A1DG01 (ACUK_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription activator of gluconeogenesis acuK
Gene names
Name:acuK
ORF Names:AN7468
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length683 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the ERT1/acuK family.

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.

Ontologies

Keywords
   Biological processGluconeogenesis
Transcription
Transcription regulation
   Cellular componentNucleus
   LigandDNA-binding
Metal-binding
Zinc
   Molecular functionActivator
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

sequence-specific DNA binding RNA polymerase II transcription factor activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 683683Transcription activator of gluconeogenesis acuK
PRO_0000406442

Regions

DNA binding65 – 9329Zn(2)-C6 fungal-type

Sequences

Sequence LengthMass (Da)Tools
A1DG01 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 1DD243D44C14C210

FASTA68374,236
        10         20         30         40         50         60 
MKTEDNGSAP ALAGDHGGVD QDTPDAGDRT EQAKHKTNGT TEKAPKSSNA KDPSRPRRKK 

        70         80         90        100        110        120 
ARRACFACQR AHLTCGDERP CQRCIKRGLQ DACHDGVRKK AKYLHDAPDG ALMPGVGGNF 

       130        140        150        160        170        180 
YNNAMRNNLP LSRNGATTVN TTSQQNSGSS YYPTPQSNSY NVYQDTPLTQ NSFPSQSPVS 

       190        200        210        220        230        240 
PTFNMKTTPT ARSNSLSSSV NQQPPNTTVS GATQSQNPFA GPFFDPSDPA LFNFDLSSMN 

       250        260        270        280        290        300 
FENRYGALEF GMLGHMATGA GDSPTDSATQ RGSMGRSGST QYSTTPITGA PGFGESPGNQ 

       310        320        330        340        350        360 
QPFMFGNDPL LNEWPNSQAP NQGHLNVSGV YPQGGMMHMA KSDAPHAFAI ESGPASFSSP 

       370        380        390        400        410        420 
SATTSPHINS GYDESSLSNT VVNKSNGLTA NGQRPAITTP SLKHQSLQFG VKRRQRNPST 

       430        440        450        460        470        480 
VYESVKEPYA YTNRFHNLTA FIQRRFSPQK TLQIAKALAS IRPSFIATTK TLNRDDLIFM 

       490        500        510        520        530        540 
EKCFQRTLWE YEDFINACGT PTIVCRRTGE IAAVGKEFSI LTGWKKDVLL GKEPNLNVNT 

       550        560        570        580        590        600 
GGSSAPGSGT TSRGSFTPRS STLENATPGR PQPVFLAELL DDDSVVEFYE DFARLAFGDS 

       610        620        630        640        650        660 
RGSVMTTCKL LKYKTKEDME LAQSDDNQRW NNHLRKGGIA GEAGMNQLGF KDGKVECAYC 

       670        680 
WTVKRDVFDI PMLIVMNVSC QCF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW18308.1.
RefSeqXP_001260205.1. XM_001260204.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING36630.CADNFIAP00007576.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00007743; CADNFIAP00007576; CADNFIAG00007743.
GeneID4586762.
KEGGnfi:NFIA_082550.

Phylogenomic databases

eggNOGNOG39365.
HOGENOMHOG000162694.
OMALGHMSSG.
OrthoDBEOG70KGZB.

Family and domain databases

Gene3D4.10.240.10. 1 hit.
InterProIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMSSF57701. SSF57701. 1 hit.
PROSITEPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACUK_NEOFI
AccessionPrimary (citable) accession number: A1DG01
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families